Casson R Ian, King Will D, Godwin N Marshall S, Petrella Robert J
Department of Family Medicine, Queen's University, Kingston, Ontario, Canada.
Can J Cardiol. 2003 Dec;19(13):1485-9.
Many treated hypertensive patients have inadequate control of their blood pressure. Physical activity and cardiorespiratory fitness are important in the development and treatment of hypertension. Less is known about their relationships with hypertension control in the context of long-term management.
To identify whether patients with lower levels of activity or fitness are at risk for loss of control of hypertension.
Follow-up blood pressure measurements were recorded over the period of a year in a cohort of initially controlled hypertensive patients, under the care of 50 family physicians in a variety of practice settings. A questionnaire for a one-year recall of leisure time physical activity and the Step Test, an indirect measure of maximal oxygen consumption, were administered to the patients at the end of the period of blood pressure observations. The study group for the activity questionnaire consisted of 385 patients; 310 of whom undertook the fitness test. Sociodemographic, clinical and lifestyle factors were analyzed as potential confounders in the relationships of main interest in this study: between activity and fitness, respectively, with loss of control of hypertension.
Sixteen per cent of patients (95% CI 12, 20) had an increase of 20 mmHg systolic or 10 mmHg diastolic from baseline to the average of three follow-up blood pressures, and 14% (95% CI 11, 18) had blood pressures above the entry thresholds on at least two of three follow-up visits. No associations were found between loss of control of hypertension and physical activity or cardiorespiratory fitness.
Lower levels of physical activity and fitness are not associated with loss of hypertension control. The identification of patients at risk for loss of hypertension control, which could be useful in targeting selected groups for increased follow-up and in understanding the high prevalence of uncontrolled hypertension, requires further study.
许多接受治疗的高血压患者血压控制不佳。身体活动和心肺适能在高血压的发生和治疗中起着重要作用。在长期管理的背景下,人们对它们与高血压控制之间的关系了解较少。
确定活动水平或适能较低的患者是否有高血压控制不佳的风险。
在一年的时间里,对一组最初血压得到控制的高血压患者进行随访血压测量,这些患者由50名家庭医生在各种实践环境中进行照料。在血压观察期结束时,向患者发放一份关于一年休闲时间身体活动的问卷以及一项最大耗氧量的间接测量指标——台阶试验。活动问卷的研究组由385名患者组成;其中310人进行了适能测试。社会人口统计学、临床和生活方式因素被分析为该研究主要关注关系中的潜在混杂因素:分别是活动和适能与高血压控制不佳之间的关系。
16%的患者(95%可信区间12,20)从基线到三次随访血压平均值收缩压升高20 mmHg或舒张压升高10 mmHg,14%(95%可信区间11,18)在三次随访中的至少两次血压高于初始阈值。未发现高血压控制不佳与身体活动或心肺适能之间存在关联。
较低的身体活动水平和适能与高血压控制不佳无关。确定有高血压控制不佳风险的患者,这可能有助于针对特定群体加强随访并理解高血压控制不佳的高患病率,这需要进一步研究。