Hall Brian K
Department of Biology, Dalhousie University, Halifax, Nova Scotia, Canada B3H 4J1.
J Exp Zool B Mol Dev Evol. 2004 Jan 15;302(1):5-18. doi: 10.1002/jez.b.20002.
The approach I have elected in this retrospective of how I became a student of evo-devo is both biographical and historical, a case study along the lines of Waddington's The Evolution of an Evolutionist ('75), although in my case it is the Evolution of an Evo-devoist. What were the major events that brought me to developmental biology and from there to evo-devo? They were, of course, specific to my generation, to the state of knowledge at the time, and to my own particular circumstances. Although exposed to evolution and embryology as an undergraduate in the 1960s, my PhD and post-PhD research programme lay within developmental biology until the early 1970s. An important formative influence on my studies as an undergraduate was the work of Conrad Hal Waddington (1905-1975), whose writings made me aware of genetic assimilation and gave me an epigenetic approach to my developmental studies. The switch to evo-devo (and my discovery of the existence of the neural crest), I owe to an ASZ (now SICB) symposium held in 1973.
在这次关于我如何成为一名演化发育生物学研究者的回顾中,我所采用的方法兼具传记性和历史性,类似于沃丁顿的《一位进化论者的演变》(1975年)的案例研究,不过在我这里是“一位演化发育生物学家的演变”。是哪些重大事件把我带入发育生物学领域,并从那里引领我走向演化发育生物学的呢?当然,这些事件与我这一代人、当时的知识状况以及我个人的特殊情况有关。尽管在20世纪60年代本科阶段我就接触到了进化和胚胎学,但直到20世纪70年代初,我的博士和博士后研究项目都属于发育生物学范畴。康拉德·哈尔·沃丁顿(1905 - 1975)的工作对我本科学习产生了重要的 formative 影响,他的著作让我了解到遗传同化,并为我的发育研究提供了一种表观遗传学方法。我转向演化发育生物学(以及我发现神经嵴的存在),要归功于1973年举行的一次美国动物学会(现为综合与比较生物学学会)研讨会。