Apaydin Erol S, Torabinejad Mahmoud
Department of Endodontics, Loma Linda School for Dentistry, Loma Linda University, CA 92350, USA.
J Endod. 2004 Jan;30(1):17-20. doi: 10.1097/00004770-200401000-00003.
The purpose of this study was to determine the effect of calcium sulfate (CS) on cementum deposition and osseous healing after periradicular surgery. The root canals of 24 mandibular premolars in four 2-yr-old beagle dogs were endodontically treated, followed 2 weeks later by periradicular surgery. Mineral trioxide aggregate (MTA) was used as root-end-filling material. The right or left side was assigned at random to receive CS alpha-hemihydrate or no material in the osteotomy sites before closure. The animals were killed after 4 months. Hard-tissue healing was analyzed histomorphometrically. All samples displayed evidence of cementum deposition adjacent to the root-end fillings and bone regeneration in the osteotomy sites. The data was analyzed using the Mann-Whitney U test, comparing the scores for cementum and osseous healing of the two groups at significance level of alpha = 0.05. The results indicated that placement of CS in osteotomy sites after periradicular surgery does not significantly affect periradicular healing.
本研究的目的是确定硫酸钙（CS）对根尖周手术后牙骨质沉积和骨愈合的影响。对4只2岁比格犬的24颗下颌前磨牙进行根管治疗，2周后进行根尖周手术。使用矿物三氧化物凝聚体（MTA）作为根尖充填材料。在关闭创口前，随机分配右侧或左侧在截骨部位接受CS半水硫酸钙或不使用任何材料。4个月后处死动物。采用组织形态计量学分析硬组织愈合情况。所有样本均显示根尖充填物附近有牙骨质沉积以及截骨部位有骨再生的迹象。使用曼-惠特尼U检验分析数据，在α = 0.05的显著性水平下比较两组牙骨质和骨愈合的评分。结果表明，根尖周手术后在截骨部位放置CS对根尖周愈合没有显著影响。
