Clinical signifcans of longitudinal determination of immunoglobulin values in infants with acut respiratory diseases.

The immunoglobulin values (IgM, IgA, IgG) were determined longitudinally in 73 infant with acute obstructive bronchitis; with acute obstructive bronchitis associated with bronchopneumonia; with bronchopneumonia. The immunoglobulin values were determined by single radial immunodiffusion method. The comparison of time of clinical recovery and x-ray clearing on the one hand and the normalisation of immunoglobulin values on the other hand was done too. It was found that the high immunoglobulin values were maintained after the clinical recovery and x-ray clearing the longest period of time in infants with acut obstructive bronchitis. In infants with acute obstructive bronchitis associated with bronchopneumonia the high immunoglobulin values were maintained very long but they were normalised on the 34-30th day of clinical recovery and x-ray clearing. In infants with bronchopneumonia the high immunoglobulin values were maintain considerably shorter and they were normalised on the 6th day after the clinical recovery. Whit regard to different time of normalisation of immunoglobulin values in infants with acute obstructive bronchitis associated with bronchopneumonia it was concluded that the longitudinal determination of immunoglobulin values has clinical significance since it can be found which of these two diseases is dominant.