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肝细胞癌的手术切除。欧洲的术后结果及长期疗效:综述

Surgical resection of hepatocellular carcinoma. Post-operative outcome and long-term results in Europe: an overview.

作者信息

Jaeck Daniel, Bachellier Philippe, Oussoultzoglou Elie, Weber Jean-Christophe, Wolf Philippe

机构信息

Centre de Chirurgie Viscérale et de Transplantation, Hôpital Universitaire de Hautepierre, Avenue Molière, Strasbourg Cedex, France.

出版信息

Liver Transpl. 2004 Feb;10(2 Suppl 1):S58-63. doi: 10.1002/lt.20041.

DOI:10.1002/lt.20041
PMID:14762841
Abstract

A multicenter retrospective review of 1467 patients treated by liver resection (LR) for hepatocellular carcinoma (HCC) in Europe over a 13-year period showed a mean mortality rate of 10.6%, which was correlated with the extent of LR, the etiology of cirrhosis and the study period with an improvement during the last years. Improved 5-year overall survival (20-51%) and disease-free survival (20-33%) reached similar rates in cirrhotic than in non-cirrhotic patients. Overall results were similar to those reported in Asian series as far as patients and tumor characteristics were comparable.

摘要

一项对欧洲1467例接受肝切除术(LR)治疗肝细胞癌(HCC)患者进行的为期13年的多中心回顾性研究显示,平均死亡率为10.6%,这与肝切除范围、肝硬化病因以及研究时期相关,且在过去几年有所改善。肝硬化患者和非肝硬化患者的5年总生存率(20%-51%)和无病生存率(20%-33%)改善后达到相似水平。就患者和肿瘤特征具有可比性而言,总体结果与亚洲系列报道的结果相似。

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