Jalón Monzón Antonio, Martín Benito José Luis, García Rodríguez Jorge, Plasencia Amela Ana, Fernández Gómez Jesús María, Fernández García Maite, Rodríguez Faba Oscar, Regadera Sejas Francisco Javier
Servicio de Urología, Servicio de Genética, Hospital Universitario Central de Asturias, Oviedo, Asturias, España.
Arch Esp Urol. 2003 Dec;56(10):1127-32.
We report 2 cases of Sertoli cell only syndrome and perform a bibliographic review.
Clinical and pathologic study of 2 male patients 33 and 37-year-old respectively who presented with infertility.
Testicular biopsy, the most important diagnostic test in the study of infertile men, showed bilateral Sertoli cell only syndrome.
The Sertoli cell only syndrome is an entity in which seminiferous tubules show a total absence of germ cells with Sertoli cells alone. Etiology is unknown in most cases. Testicular biopsy is performed in these azoospermic men to rule out tubular obstruction or abnormalities of the spermatogenesis. Assisted reproduction techniques are a therapeutic option, making genetic counselling necessary due to the risk of transmission of the genetic defects that cause male infertility.
我们报告2例支持细胞仅存综合征病例并进行文献复习。
对2例分别为33岁和37岁的男性不育患者进行临床和病理研究。
睾丸活检是男性不育研究中最重要的诊断检查，显示双侧支持细胞仅存综合征。
支持细胞仅存综合征是一种曲细精管中完全缺乏生殖细胞而仅有支持细胞的病症。大多数情况下病因不明。对这些无精子症男性进行睾丸活检以排除管道阻塞或精子发生异常。辅助生殖技术是一种治疗选择，由于存在导致男性不育的遗传缺陷传递风险，因此需要进行遗传咨询。
