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儿童期体脂分布与心血管危险因素有关吗?

Is body fat distribution associated with cardiovascular risk factors in childhood?

作者信息

Sangi H, Mueller W H, Harrist R B, Rodriguez B, Grunbaum J G, Labarthe D R

机构信息

University of Texas Health Science Center, School of Public Health, Houston.

出版信息

Ann Hum Biol. 1992 Nov-Dec;19(6):559-78. doi: 10.1080/03014469200002382.

DOI:10.1080/03014469200002382
PMID:1476412
Abstract

The authors studied the association of cardiovascular risk variables with body fat distribution (BFD) in a cross-sectional sample of 743 Texas schoolchildren of both sexes ages 6-14 years. This association is well known in adults and several useful indices of BFD are available. Whether they are applicable to children remains a question of importance for epidemiological investigations in this age group. Canonical correlations between anthropometric (five skinfolds, four circumferences) and risk (blood pressures, cholesterol, pulse) variables ranged from 0.37 to 0.82 depending on sex/age group (p < 0.01). The skinfold vector suggested an association of risk with central fat at most but not all ages. The circumference vectors, on the other hand, suggest that size or fatness, not BFD, was related to risk. Partial correlation and stepwise regression of fatness and BFD indices with cardiovascular risk factors as dependent variables, showed that 'fatness' or 'size' was more clearly associated with risk factors than BFD. The variables most consistently entering the regression were hip circumference and sum of skinfolds. These results contrast with studies of adults or sexually mature adolescents, in which BFD is more clearly related to CV risk variables and the hip circumference is a 'low-risk' variable.

摘要

作者在一个由743名6至14岁的得克萨斯州学童组成的横断面样本中,研究了心血管风险变量与身体脂肪分布(BFD)之间的关联。这种关联在成年人中已广为人知,并且有几种有用的BFD指标。它们是否适用于儿童,对于该年龄组的流行病学调查而言,仍然是一个重要问题。人体测量学变量(五个皮褶厚度、四个周长)与风险变量(血压、胆固醇、脉搏)之间的典型相关系数在0.37至0.82之间,具体取决于性别/年龄组(p < 0.01)。皮褶厚度向量表明,在大多数但并非所有年龄段,风险与中心脂肪有关。另一方面,周长向量表明,与风险相关的是体型或肥胖程度,而非BFD。以心血管风险因素为因变量,对肥胖程度和BFD指标进行偏相关分析和逐步回归分析,结果显示,与BFD相比,“肥胖程度”或“体型”与风险因素的关联更为明显。最常进入回归方程的变量是臀围和皮褶厚度总和。这些结果与针对成年人或性成熟青少年的研究形成对比,在这些研究中,BFD与心血管风险变量的关系更为明显,且臀围是一个“低风险”变量。

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Is body fat distribution associated with cardiovascular risk factors in childhood?儿童期体脂分布与心血管危险因素有关吗?
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引用本文的文献

1
Obesity, body fat distribution, and ambulatory blood pressure in children and adolescents.儿童和青少年的肥胖、体脂分布与动态血压
J Clin Hypertens (Greenwich). 2001 Nov-Dec;3(6):362-7. doi: 10.1111/j.1524-6175.2001.00492.x.
2
Blood pressure during adolescence: a study among Belgian adolescents selected from a high cardiovascular risk population.青少年时期的血压:一项针对从高心血管疾病风险人群中选取的比利时青少年的研究。
Eur J Epidemiol. 1999 Oct;15(9):783-90. doi: 10.1023/a:1007670613848.