Van Nieuwenhuysen J P, D'Hoore W
Département de Médecine Dentaire et Stomatologie, Université Catholique de Louvain, Bruxelles, Belgique.
Arch Fr Pediatr. 1992 Aug-Sep;49(7):617-21.
While fluoridation is the most effective preventive measure against dental caries, it increases the risk of tooth mottling or fluorosis.
A total of 2,003 children aged 5 to 21 years were examined by a dentist following the recommendations of WHO and the standardized system of Möller and Poulsen, including X-ray investigation. The clinical aspects of fluorosis were classified on a 5-point scale. Data on the medical history, socioeconomic conditions, oral hygiene, carbohydrate ingestion and fluoride supplements of these patients were also collected.
The majority of the 2,003 children, 1687 (84.2%), had never received dietary fluoride supplements. Only 93 (4.64% of the total) of the 316 children who had taken fluoride, regularly ingested the recommended daily dose of 1.0 mg F-. This group had 43.2% fewer incidents of tooth decay, and came from the higher socioeconomic environment. Tooth mottling was 9.58 times more frequent in this group of correctly protected children. However, the clinical aspects of fluorosis were minor, with no esthetic damage.
These results suggest that the fluoride dosage regimen commonly proposed is effective against dental caries and does not need any change to reduce the risk of fluorosis.
虽然氟化物是预防龋齿最有效的措施，但它会增加牙齿斑纹或氟斑牙的风险。
按照世界卫生组织的建议以及默勒和保尔森的标准化系统，包括X线检查，由一名牙医对总共2003名5至21岁的儿童进行了检查。氟斑牙的临床症状按5级分类。还收集了这些患者的病史、社会经济状况、口腔卫生、碳水化合物摄入及氟补充剂的数据。
2003名儿童中的大多数，即1687名（84.2%）从未接受过膳食氟补充剂。在服用氟化物的316名儿童中，只有93名（占总数的4.64%）定期摄入推荐的每日剂量1.0毫克氟离子。这组儿童的龋齿发生率低43.2%，并且来自较高的社会经济环境。在这组得到正确防护的儿童中，牙齿斑纹的发生率高9.58倍。然而，氟斑牙的临床症状较轻，未造成美观损害。
这些结果表明，通常建议的氟化物剂量方案对预防龋齿有效，并且无需改变以降低氟斑牙的风险。
