Biasotto M, Cadenaro M, Di Lenarda R
Dipartimento di Scienze Chirurgiche Specialistiche, Universtà degli Studi di Trieste, Trieste, Italy.
Minerva Stomatol. 2003 Dec;52(11-12):531-4.
Actinomycosis is currently an uncommonly diagnosed human disease. The disease is a chronic suppurative infection caused by micro-organism from the Actinomyces group, most often Israelii. A patient with cervicofacial actinomycosis generally reports a history of recent dental treatment which, usually, involves extraction of a mandibular molar. The common initial signs and symptoms of infection (such as sudden onset of cervicofacial pain, swelling, erythema, edema and suppuration) can be absent. In this case report a 29-year-old man presented a mass in his left parotid area, 1 week after mandibular molar extraction. Echography and CT scans revealed a parotid abscess area. The needle-biopsy of swelling revealed infection due to Actinomyces. Therapy was started with intravenous cefazolin (fl 1g X 2 in 100 s.s. i.v.) and methylprednisolone (25 mg tablet, 1/die) for 9 days; 14 days after treatment suspension the lesion reappeared with a fistula and a new therapy was given (ceftriaxone 1 g/die and gentamicin 80 mg/i.m. for 3 weeks). To prevent a relapse, the patient received cefalexin 1 gx2/die per os for 4 weeks. After a follow-up of 1 year, the patient was still asymptomatic.
放线菌病是目前一种诊断不常见的人类疾病。该疾病是由放线菌属微生物引起的慢性化脓性感染,最常见的是以色列放线菌。患有颈面部放线菌病的患者通常报告近期有牙科治疗史,通常涉及下颌磨牙拔除。感染的常见初始体征和症状(如颈面部疼痛、肿胀、红斑、水肿和化脓的突然发作)可能不存在。在本病例报告中,一名29岁男性在拔除下颌磨牙1周后,左侧腮腺区出现肿块。超声检查和CT扫描显示腮腺脓肿区域。肿胀部位的针吸活检显示为放线菌感染。治疗开始时静脉注射头孢唑林(1g×2,溶于100ml生理盐水中静脉注射)和甲基泼尼松龙(25mg片剂,每日1次),持续9天;停药14天后,病变复发并出现瘘管,于是给予新的治疗(头孢曲松1g/日和庆大霉素80mg肌肉注射,持续3周)。为防止复发,患者口服头孢氨苄1g×2/日,持续4周。经过1年的随访,患者仍无症状。