Lang-Roth R, Schippers C, Eckel H E
Klinik für Hals-Nasen-Ohren Heilkunde, Universität zu Köln.
HNO. 1998 Apr;46(4):354-8. doi: 10.1007/s001060050252.
Actinomycosis is currently an uncommonly diagnosed human disease. However, it can still complicate trauma to the respiratory and digestive tracts, including operative procedures. A patient with cervicofacial actinomycosis commonly gives a history of recent dental manipulation which usually, involves extraction of a mandibular molar. The common initial symptoms of infection--such as, sudden onset of cervicofacial pain, swelling, erythema, edema and suppuration--can be absent. Infection due to actinomyces is a well-known mimic of malignancy is clinical, radiological and pathological findings. In the case described a 65-year-old man had a mass in his right parotid area. Because of its painless rapid growth with infiltration of the mandible as demonstrated by clinical findings and CT and MRI scans, we established an initial diagnosis of salivary gland malignancy. Salivary gland biopsy then revealed a histological picture of infection due to actinomyces. Therapy was initiated with intravenous amoxicillin and sulbactam. After 20 days of treatment diseased soft tissues and bone were resected. To prevent a relapse the patient received oral clindamycin for 6 weeks. After a followup of two years, the patient has remained free of disease.
放线菌病目前是一种诊断不常见的人类疾病。然而,它仍可使呼吸道和消化道创伤(包括手术操作)复杂化。患有颈面部放线菌病的患者通常有近期牙科操作史,通常涉及下颌磨牙拔除。感染的常见初始症状,如颈面部突然疼痛、肿胀、红斑、水肿和化脓,可能不存在。放线菌感染在临床、放射学和病理学表现上是众所周知的恶性肿瘤模仿者。在所描述的病例中,一名65岁男性右侧腮腺区有一肿块。由于临床检查、CT和MRI扫描显示其无痛性快速生长并侵犯下颌骨,我们初步诊断为涎腺恶性肿瘤。涎腺活检随后显示出放线菌感染的组织学图像。开始用静脉注射阿莫西林和舒巴坦治疗。治疗20天后,切除患病的软组织和骨骼。为防止复发,患者接受了6周的口服克林霉素治疗。经过两年的随访,患者一直无病。