Bernasconi Enos, Valsangiacomo Claudio, Peduzzi Raffaele, Carota Antonio, Moccetti Tiziano, Funke Guido
Infectious Disease Unit, Department of Internal Medicine, Hospital of Lugano, Lugano, Switzerland.
Clin Infect Dis. 2004 Feb 15;38(4):e27-31. doi: 10.1086/381436. Epub 2004 Jan 28.
We report a case of endocarditis due to Arthrobacter woluwensis and review the published reports of Arthrobacter species isolated from human clinical samples. A 39-year-old injection drug user presented with fever and a new heart murmur. A. woluwensis was isolated from blood cultures, and a diagnosis of subacute infective endocarditis of the native mitral valve was made. The patient was successfully treated with a 6-week course of intravenous teicoplanin. From our review of the literature, we were able to retrieve data on 41 cases of Arthrobacter species isolated from human clinical samples. However, Arthrobacter species was documented as a cause of human disease on only 5 other occasions (2 cases of bacteremia, 1 case of postoperative endophthalmitis, 1 case of a Whipple disease-like syndrome, and 1 case of phlebitis). Because of the difficulty of identifying Arthrobacter strains by conventional biochemical assays, it is likely that infections with these coryneform bacteria are underreported.
我们报告了一例由沃卢韦节杆菌引起的心内膜炎病例，并回顾了已发表的从人类临床样本中分离出节杆菌属细菌的报告。一名39岁的注射吸毒者出现发热和新的心脏杂音。从血培养中分离出了沃卢韦节杆菌，诊断为原发性二尖瓣亚急性感染性心内膜炎。该患者接受了为期6周的静脉注射替考拉宁治疗，治疗成功。通过对文献的回顾，我们能够检索到41例从人类临床样本中分离出节杆菌属细菌的数据。然而，节杆菌属细菌仅在其他5例病例中被记录为人类疾病的病因（2例菌血症、1例术后眼内炎、1例类惠普尔病综合征和1例静脉炎）。由于通过传统生化检测鉴定节杆菌菌株存在困难，这些棒状杆菌感染很可能未得到充分报告。
