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使用腔内自膨式胆管壁支架治疗犬晚期气管塌陷

Management of advanced tracheal collapse in dogs using intraluminal self-expanding biliary wallstents.

作者信息

Moritz Andreas, Schneider Matthias, Bauer Natali

机构信息

Clinic for Internal Medicine and Forensic Affairs, Justus-Liebig-University Giessen, Germany.

出版信息

J Vet Intern Med. 2004 Jan-Feb;18(1):31-42. doi: 10.1892/0891-6640(2004)18<31:moatci>2.0.co;2.

Abstract

Twenty-four client-owned dogs with tracheal collapse refractory to conventional treatment underwent management with an intraluminal self-expanding stainless-steel endoprosthesis (Wallstent). Initial improvement of clinical signs was observed in 95.8% of the dogs. Two dogs (8.3%) died within a median interval of 6 days after stent implantation due to incorrect placement and size of the stent and emphysema, respectively. A dry cough occurred temporarily in most of the patients. One dog each (4.1%) suffered mild transient tracheal hemorrhage and pneumomediastinum. The results showed that the initial survival rate of intraluminal stabilization was comparable with surgical implantation of extratracheal prostheses. Clinical reevaluation was performed in 18 dogs within a median interval of 68 days after treatment. Of the dogs treated, 30.4% were reported to be asymptomatic after stent implantation, 60.9% improved markedly, and 4.3% remained symptomatic. In all patients undergoing endoscopy, the Wallstents were almost completely covered with tracheal epithelium. A median shortening of 27.3% of the endoprosthesis within a median interval of 175 days after stent implantation in 15 of 18 dogs was noted. The shortening was associated with clinical signs in 2 patients. In 5 dogs, steroid-responsive granuloma formation resulted in a severe reduction of the tracheal lumen in 3 patients. The results suggest that implantation of Wallstents was minimally invasive and provided stabilization of collapsed thoracic tracheal portions in addition to the cervical part of the trachea. This minimally invasive method for the management of severe tracheal collapse therefore provides an attractive alternative to surgery.

摘要

24只患有传统治疗无效的气管塌陷的宠物犬接受了腔内自膨式不锈钢内支架(Wallstent)治疗。95.8%的犬临床症状出现初步改善。两只犬(8.3%)分别因支架放置不当和尺寸问题以及肺气肿在支架植入后中位间隔6天内死亡。大多数患者出现了暂时性干咳。各有一只犬(4.1%)出现轻度短暂性气管出血和气纵隔。结果显示,腔内稳定治疗的初始存活率与气管外假体手术植入相当。18只犬在治疗后中位间隔68天进行了临床重新评估。在接受治疗的犬中,30.4%在支架植入后无症状,60.9%明显改善,4.3%仍有症状。在所有接受内镜检查的患者中,Wallstent几乎完全被气管上皮覆盖。在18只犬中的15只犬支架植入后中位间隔175天内,内支架中位缩短了27.3%。缩短与2例患者的临床症状相关。在5只犬中,类固醇反应性肉芽肿形成导致3例患者气管腔严重缩小。结果表明,Wallstent植入微创,除了气管颈段外,还能稳定塌陷的胸段气管部分。因此,这种治疗严重气管塌陷的微创方法为手术提供了有吸引力的替代方案。

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