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下肢关节置换术并发深静脉血栓形成。患病率及主观结果。

Lower limb arthroplasty complicated by deep venous thrombosis. Prevalence and subjective outcome.

作者信息

Cordell-Smith J A, Williams S C, Harper W M, Gregg P J

机构信息

University Hospitals of Leicester, England.

出版信息

J Bone Joint Surg Br. 2004 Jan;86(1):99-101.

Abstract

The aim of this study was to determine the prevalence of deep venous thrombosis (DVT) following lower limb arthroplasty and to assess whether this adversely affected satisfaction, relief from pain, or the level of mobility as perceived by patients. Six hundred and ten consecutive recipients of primary total hip replacement (THR) or total knee replacement (TKR) underwent routine post-operative venography. The functional outcome had already been assessed at one year by using the Regional Arthroplasty Database questionnaire, the results of which were correlated to venographic records. The combined prevalence of DVT after THR and TKR in the patients, who did not receive chemical thromboprophylaxis, was 46.4%. Thrombus was identified in 57.6% of those with a TKR and in 33.5% of patients with a THR. Proximal thrombus was found in 11.0% of TKRs and in 14.8% of THRs. One year after surgery, patients who had a DVT established by venography did not report higher levels of immobility (p = 0.07), discomfort (p = 0.12) or dissatisfaction (p = 0.23) when compared to those with patent venous systems. This suggests that the prevalence of DVT following TKR/THR without chemical thromboprophylaxis is high and these findings are consistent with the literature. However, patients did not perceive thrombosis to compromise their overall outcome. This challenges the belief that DVT is associated with morbidity and calls for further comprehensive research in this area. The low morbidity of the lower limb associated with DVT in these patients does not support the use of chemical thromboprophylaxis.

摘要

本研究的目的是确定下肢关节置换术后深静脉血栓形成(DVT)的发生率,并评估其是否会对患者的满意度、疼痛缓解情况或活动能力产生不利影响。610例连续接受初次全髋关节置换术(THR)或全膝关节置换术(TKR)的患者接受了常规术后静脉造影。使用区域关节置换数据库问卷在术后一年对功能结果进行了评估,其结果与静脉造影记录相关。在未接受化学血栓预防的患者中,THR和TKR后DVT的合并发生率为46.4%。在TKR患者中有57.6%发现血栓,在THR患者中有33.5%发现血栓。在TKR患者中有11.0%发现近端血栓,在THR患者中有14.8%发现近端血栓。术后一年,与静脉系统通畅的患者相比,经静脉造影确诊患有DVT的患者在活动不便(p = 0.07)、不适(p = 0.12)或不满意(p = 0.23)方面并未报告更高的水平。这表明在未进行化学血栓预防的TKR/THR后DVT的发生率很高,这些发现与文献一致。然而,患者并未感觉到血栓形成会损害其总体结果。这对DVT与发病率相关这一观点提出了挑战,并呼吁在该领域进行进一步的全面研究。这些患者中与DVT相关的下肢低发病率不支持使用化学血栓预防措施。

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