在感染循环重组形式A/G（CRF02）的患者中，将LCx与其他当前病毒载量检测方法用于检测和定量1型人类免疫缺陷病毒RNA的比较。
Comparison of LCx with other current viral load assays for detecting and quantifying human immunodeficiency virus type 1 RNA in patients infected with the circulating recombinant form A/G (CRF02).
作者信息
Amendola Alessandra, Bordi Licia, Angeletti Claudio, Girardi Enrico, Ippolito Giuseppe, Capobianchi Maria R
机构信息
National Institute for Infectious Diseases "Lazzaro Spallanzani," Rome, Italy.
出版信息
J Clin Microbiol. 2004 Feb;42(2):811-5. doi: 10.1128/JCM.42.2.811-815.2004.
Abstract
LCx was compared to other assays in measuring human immunodeficiency virus type 1 (HIV-1) CRF02 viremia. LCx showed significant but low correlation with the other methods. Values of <2.60 log(10) cp/ml were observed in 29.6% of specimens with LCx and in only 14.8% with bDNA and PCR, suggesting suboptimal performance of LCx with CRF02.
摘要
在测量1型人类免疫缺陷病毒（HIV-1）CRF02病毒血症方面，将LCx与其他检测方法进行了比较。LCx与其他方法显示出显著但较低的相关性。使用LCx检测时，29.6%的标本检测值<2.60 log(10) cp/ml，而使用分支DNA（bDNA）和聚合酶链反应（PCR）检测时，这一比例仅为14.8%，提示LCx对CRF02的检测性能欠佳。
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