Kaneko Hiroaki, Tomomasa Takeshi, Kubota Yumi, Todokoro Makoto, Kato Masahiko, Miyazawa Reiko, Suzuki Tomoko, Hatori Yukie, Kunimoto Fumio, Yamamoto Koujirou, Morikawa Akihiro
Department of Pediatrics, Gunma University School of Medicine, 3-39-15 Showa-machi, Maebashi 371-8511, Japan.
J Gastroenterol. 2004 Jan;39(1):69-71. doi: 10.1007/s00535-003-1247-z.
We encountered a gastric bezoar that had developed in a 9-year-old girl treated with sodium alginate (Alloid G) for acute gastritis associated with systemic lupus erythematosus. A hard mass palpated in the left upper abdomen proved, upon gastric endoscopy, to be an intragastric foreign body. Sodium alginate was detected in an analysis of a sample from this bezoar. In an in vitro simulation, sodium alginate solidified when mixed with the patient's other medicines. The bezoar caused no complications, and disappeared spontaneously after discontinuation of the medications. This case indicates that this sodium alginate preparation, Alloid G, can be a cause of pharmacobezoar.
我们遇到了一例胃石症，该病例发生在一名9岁女孩身上，她因系统性红斑狼疮伴发的急性胃炎而接受海藻酸钠（Alloid G）治疗。左上腹可触及的硬块经胃镜检查证实为胃内异物。对该胃石样本的分析检测到了海藻酸钠。在体外模拟实验中，海藻酸钠与患者的其他药物混合后会凝固。该胃石未引起并发症，停药后自行消失。此病例表明，这种海藻酸钠制剂Alloid G可能是药物性胃石的一个病因。
