Métneki J, Pazonyi I, Czeizel A
Department of Human Genetics and Teratology, WHO Collaborating Centre for the Community Control of Hereditary Diseases, National Institute of Hygiene, Budapest, Hungary.
Acta Paediatr Hung. 1992;32(3):203-17.
Of 1038 index patients with multiple congenital abnormalities, 34 were twins. This 3.3 per cent is higher than the Hungarian birth rate of about 2.1 per cent. However, after the exclusion of cases with congenital abnormality association of low birth weight newborn infants and with genital anomalies of the male, the twin birth rate was 1.8 per cent. Thus, the unidentified multiple congenital abnormalities have no common cause with twinning.
在1038例患有多种先天性异常的索引患者中,有34例是双胞胎。3.3%这一比例高于匈牙利约2.1%的出生率。然而,在排除低体重新生儿先天性异常关联病例和男性生殖器异常病例后,双胞胎出生率为1.8%。因此,不明原因的多种先天性异常与双胞胎现象没有共同的成因。