O'Dea R F
NAACOGS Clin Issu Perinat Womens Health Nurs. 1992;3(4):598-604.
Historically, the risks associated with drugs in breast milk were not a major clinical concern. The small percentage of infants who were breastfed and the low use of drugs in postpartum women stimulated little interest in studying medication use in the breastfeeding mother. However, explosive growth in the number of new pharmacologic agents, concerns over environmental contaminants, and a significant increase in breastfeeding, dramatically altered the interest in this clinical issue. Providers of health care to women and children often are asked to advise breastfeeding women on the choice and risks of a particular medication. However, medical professionals too often simply discourage breastfeeding when this situation arises. This short review examines factors that determine whether a drug that enters breast milk poses a risk to the breastfeeding infant. A series of questions and practical decisions are presented that should enable nurses and other health care providers to more effectively address the issue of medication use in a breastfeeding woman.
从历史上看,母乳中药物相关的风险并非主要临床关注点。母乳喂养的婴儿比例较小,且产后女性用药率较低,这使得对母乳喂养母亲用药情况的研究兴趣寥寥。然而,新型药物数量的迅猛增长、对环境污染物的担忧以及母乳喂养率的显著上升,极大地改变了人们对这一临床问题的关注。为妇女和儿童提供医疗保健服务的人员经常被要求就特定药物的选择和风险向母乳喂养的妇女提供建议。然而,当出现这种情况时,医疗专业人员往往只是简单地劝阻母乳喂养。这篇简短的综述探讨了决定进入母乳的药物是否会对母乳喂养的婴儿构成风险的因素。文中提出了一系列问题和实际决策,应能使护士和其他医疗保健人员更有效地处理母乳喂养妇女的用药问题。