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人乳中的药物和化学物质。

Drugs and chemicals in human milk.

作者信息

Berlin Cheston M, Briggs Gerald G

机构信息

Penn State Children's Hospital, MS Hershey Medical Center, PO Box 850, 500 University Drive, Hershey, PA 17033-0850, USA.

出版信息

Semin Fetal Neonatal Med. 2005 Apr;10(2):149-59. doi: 10.1016/j.siny.2004.09.016. Epub 2004 Dec 21.

Abstract

There is continuing emphasis by many professionals and organizations on the importance of breastfeeding as optimal infant nutrition. Pediatricians are frequently asked about the safety of medications taken by the nursing mother and the risk to the infant. Most drugs and many chemicals will be transferred into milk. For a vast majority of these compounds, there is no risk to the infant. It is almost always possible for the mother to continue nursing while taking the necessary medication. This article presents an introduction to the pharmacology of the transfer of drugs into milk, discusses the importance of the infant's age in assessing safety and presents a number of maternal conditions for which drugs need to be used.

摘要

许多专业人士和组织持续强调母乳喂养作为最佳婴儿营养方式的重要性。儿科医生经常被问及哺乳期母亲所服用药物的安全性以及对婴儿的风险。大多数药物和许多化学物质都会转移到乳汁中。对于绝大多数此类化合物而言,对婴儿并无风险。母亲在服用必要药物时几乎总能继续哺乳。本文介绍了药物向乳汁转移的药理学知识,讨论了婴儿年龄在评估安全性方面的重要性,并列举了一些需要用药的母亲的情况。

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