Suzuki Asuka, Kumashiro Ryukichi, Shirachi Miki, Kuroki Mina, Suzuki Hiroshi, Tanikawa Kyuichi, Sata Michio
Department of Medicine, Kurume University School of Medicine, 67 Asahi-machi, Kurume 830-0011, Japan.
Kurume Med J. 2003;50(3-4):155-9. doi: 10.2739/kurumemedj.50.155.
We treated a patient simultaneously infected with hepatitis E virus and Leptospira interrogans, both acquired in China. Severe hyperbilirubinemia required nearly 200 days to resolve, transminase elevation showed a fluctuating course, and liver biopsy specimens showed fibrosis unusual for hepatitis E. Leptospirosis appeared to have altered the course of hepatitis E virus infection in this patient, even though infection with Leptospira was cleared with antibiotics by 50 days after the onset of the hepatitis symptoms.
我们治疗了一名同时感染戊型肝炎病毒和问号钩端螺旋体的患者，两种感染均发生在中国。严重的高胆红素血症需要近200天才能消退，转氨酶升高呈波动过程，肝活检标本显示出戊型肝炎不常见的纤维化。钩端螺旋体病似乎改变了该患者戊型肝炎病毒感染的病程，尽管在肝炎症状出现后50天，钩端螺旋体感染已通过抗生素清除。
