Johnston Josephine, Thomas Mark
The Hastings Center, 21 Malcolm Gordon Road, Garrison, New York 10524, USA.
Dev World Bioeth. 2003 Dec;3(2):103-8. doi: 10.1046/j.1471-8731.2003.00064.x.
This summary lays out the basic science and methodology used in genetic testing that investigates historical population migrations and the ancestry of living individuals. The genetic markers used in this testing, and the distinction between Y-chromosome, mitochondrial and autosomes analysis, are explained and the shortcomings of these methodologies are explored.
本综述阐述了基因检测中用于研究历史人口迁移和当代个体祖先的基础科学及方法。文中解释了该检测中使用的基因标记,以及Y染色体、线粒体和常染色体分析之间的区别,并探讨了这些方法的不足之处。