Flores Carlos, Maca-Meyer Nicole, González Ana M, Oefner Peter J, Shen Peidong, Pérez Jose A, Rojas Antonio, Larruga Jose M, Underhill Peter A
Departamento de Genética, Universidad de La Laguna, Tenerife E-38271, Spain.
Eur J Hum Genet. 2004 Oct;12(10):855-63. doi: 10.1038/sj.ejhg.5201225.
Europe has been influenced by both intra- and intercontinental migrations. Since the Iberian peninsula was a refuge during the Last Glacial Maximum, demographic factors associated with contraction, isolation, subsequent expansion and gene flow episodes have contributed complexity to its population history. In this work, we analysed 26 Y-chromosome biallelic markers in 568 chromosomes from 11 different Iberian population groups and compared them to published data on the Basques and Catalans to gain insight into the paternal gene pool of these populations and find out to what extent major demographic processes account for their genetic structure. Our results reveal a reduced, although geographically correlated, Y-chromosomal interpopulation variance (1.2%), which points to a limited heterogeneity in the region. Coincidentally, spatial analysis of genetic distances points to a focal distribution of Y-chromosome haplogroups in this area. These results indicate that neither old or recent Levantine expansions nor North African contacts have influenced the current Iberian Y-chromosome diversity so that geographical patterns can be identified.
欧洲受到了洲际内部和洲际间移民的影响。由于伊比利亚半岛在末次盛冰期时是一个避难所，与人口收缩、隔离、随后的扩张以及基因流动事件相关的人口因素，使得该地区的人口历史变得复杂。在这项研究中，我们分析了来自11个不同伊比利亚人群体的568条染色体上的26个Y染色体双等位基因标记，并将其与已发表的巴斯克人和加泰罗尼亚人的数据进行比较，以深入了解这些人群的父系基因库，并探究主要人口过程在多大程度上塑造了他们的遗传结构。我们的结果显示，尽管存在地理相关性，但Y染色体群体间的方差降低（1.2%），这表明该地区的异质性有限。巧合的是，遗传距离的空间分析表明该地区Y染色体单倍群呈集中分布。这些结果表明，无论是古代还是近代的黎凡特扩张，还是与北非的接触，都没有影响当前伊比利亚Y染色体的多样性，因此可以识别出地理模式。
