Juric H, Dukic W, Jankovic B, Karlovic Z, Pavelic B
Department of Pedodontics, School of Dental Medicine, University of Zagreb, Croatia.
Cent Eur J Public Health. 2003 Dec;11(4):219-22.
Reduction of cariogenic bacteria, especially salivary Streptococcus mutans and lactobacilli is a valuable clinical procedure that in many ways alleviates implementation of targeted caries preventive procedures in the entire population. The aim of this study was to investigate the caries preventive values of certain preventive procedures in in vivo conditions. Four groups of subjects, each with 18 children aged from 4-5 and 10-12 years (n = 72) were treated with different caries preventive agent (aminfluoride solution, Proxyt paste, chewing gum containing xylitol and fluoride and chlorhexidine solution). During a period of two months five control measurements for number of salivary Streptococcus mutans (SM) and lactobacilli (LB) were performed. At the end of the study the best result in the reduction of the bacteria was achieved by the application of Proxyt paste and daily use of chewing gum (p < 0.001). In patients treated with this preventive procedure the number of SM was reduced by 1 class and LB to < 10(4) CFU/ml saliva after two months of study. The results obtained indicate that professional teeth cleaning and use of chewing gum with xylitol and fluorides on daily basis can be very effective protocol for cariogenic bacteria reduction and in the individual caries prevention.
减少致龋菌，尤其是唾液中的变形链球菌和乳酸杆菌，是一项有价值的临床措施，在很多方面有助于在整个人口中实施有针对性的龋齿预防措施。本研究的目的是在体内条件下调查某些预防措施的防龋价值。四组受试者，每组有18名4至5岁和10至12岁的儿童（n = 72），分别用不同的防龋剂（氨基氟化物溶液、Proxyt糊剂、含木糖醇和氟化物的口香糖以及洗必泰溶液）进行治疗。在两个月的时间里，对唾液中变形链球菌（SM）和乳酸杆菌（LB）的数量进行了五次对照测量。研究结束时，应用Proxyt糊剂和每日使用口香糖在减少细菌方面取得了最佳效果（p < 0.001）。在接受这种预防措施治疗的患者中，经过两个月的研究，SM的数量减少了1个等级，LB减少到<10(4) CFU/ml唾液。所得结果表明，专业的牙齿清洁以及每日使用含木糖醇和氟化物的口香糖可能是减少致龋菌和预防个体龋齿的非常有效的方案。
