Litscher G
University of Graz, Department of Biomedical Engineering and Research in Anesthesia and Intensive Care, Graz, Austria.
Eur J Anaesthesiol. 2004 Jan;21(1):13-9. doi: 10.1017/s0265021504001036.
The main purpose of this study was to investigate the effects of sensory (acupressure and acupuncture) and optical stimulation (Laserneedle acupuncture) on electroencephalographic bispectral index, spectral edge frequency and a verbal sedation score.
Twenty-five healthy volunteers (mean age +/- SD: 25.5 +/- 4.0yr) were investigated during the awake state. The acupuncture point Yintang and a placebo control point were stimulated. The study was performed as a randomized, controlled and partly blinded cross-over trial.
Bispectral index and spectral edge frequency values both decreased significantly (P < 0.001) during acupressure on Yintang to values of 62.9 (minimum 35) +/- 13.9 bispectral index and to 13.3 (minimum 2.9) +/- 8.1 Hz (spectral edge frequency right) and 13.8 (minimum 2.7) +/- 7.3 Hz (spectral edge frequency left), respectively. Bispectral index was also significantly (P < 0.05) affected by Laserneedle acupuncture and acupressure on the control point but the changes were not clinically relevant, 95.4 +/- 4 and 94.2 +/- 4.8, respectively. All interventions significantly (Yintang: P < 0.001; control point: P < 0.012) reduced verbal sedation score.
The study highlights the electroencephalographic similarities of acupressure induced sedation and general anaesthesia as assessed by bispectral index and spectral edge frequency.
本研究的主要目的是探讨感觉刺激（指压和针刺）及光刺激（激光针针灸）对脑电图双谱指数、谱边缘频率及语言镇静评分的影响。
对25名健康志愿者（平均年龄±标准差：25.5±4.0岁）在清醒状态下进行研究。刺激印堂穴及一个安慰剂对照点。本研究采用随机、对照且部分盲法的交叉试验。
在对印堂进行指压时，双谱指数和谱边缘频率值均显著降低（P<0.001），双谱指数降至62.9（最低35）±13.9，谱边缘频率右侧降至13.3（最低2.9）±8.1Hz，左侧降至13.8（最低2.
