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Translational research using the sodium/iodide symporter in imaging and therapy.

作者信息

Chung June-Key, Kang Joo Hyun

出版信息

Eur J Nucl Med Mol Imaging. 2004 Jun;31(6):799-802. doi: 10.1007/s00259-004-1475-3. Epub 2004 Feb 10.

DOI:10.1007/s00259-004-1475-3
PMID:14770271
Abstract
摘要

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Translational research using the sodium/iodide symporter in imaging and therapy.利用钠/碘同向转运体进行成像和治疗的转化研究。
Eur J Nucl Med Mol Imaging. 2004 Jun;31(6):799-802. doi: 10.1007/s00259-004-1475-3. Epub 2004 Feb 10.
2
Overlooked contributions on sodium iodide symporter.碘化钠同向转运体被忽视的贡献。
J Nucl Med. 2003 Oct;44(10):1707.
3
Combining transfer of TTF-1 and Pax-8 gene: a potential strategy to promote radioiodine therapy of thyroid carcinoma.联合转染 TTF-1 和 Pax-8 基因：促进甲状腺癌放射性碘治疗的潜在策略。
Cancer Gene Ther. 2012 Jun;19(6):402-11. doi: 10.1038/cgt.2012.13. Epub 2012 Apr 13.
4
Radioiodide imaging and treatment of ARO cancer xenograft in a mouse model after expression of human sodium iodide symporter.在人钠碘转运体表达后，小鼠模型中ARO癌异种移植瘤的放射性碘成像与治疗。
Anticancer Res. 2007 Jul-Aug;27(4B):2515-22.
5
Image-guided radioiodide therapy of medullary thyroid cancer after carcinoembryonic antigen promoter-targeted sodium iodide symporter gene expression.癌胚抗原启动子靶向的碘化钠同向转运体基因表达后甲状腺髓样癌的图像引导放射性碘治疗
Hum Gene Ther. 2007 Oct;18(10):916-24. doi: 10.1089/hum.2007.081.
6
Establishment of radioactive astatine and iodine uptake in cancer cell lines expressing the human sodium/iodide symporter.在表达人钠/碘同向转运体的癌细胞系中建立放射性砹和碘摄取。
Eur J Nucl Med Mol Imaging. 2002 Jul;29(7):842-54. doi: 10.1007/s00259-002-0784-7. Epub 2002 Apr 11.
7
Evidence for transcriptional and posttranscriptional alterations of the sodium/iodide symporter expression in hypofunctioning benign and malignant thyroid tumors.甲状腺功能减退的良性和恶性甲状腺肿瘤中钠/碘同向转运体表达的转录和转录后改变的证据。
Am J Pathol. 2004 Jul;165(1):25-34. doi: 10.1016/S0002-9440(10)63272-5.
8
Requisites for successful theranostics with radionuclide-based reporter gene imaging.基于放射性核素的报告基因成像实现成功诊疗一体化的必备条件。
J Drug Target. 2014 May;22(4):295-303. doi: 10.3109/1061186X.2013.878940. Epub 2014 Jan 13.
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Preclinical efficacy of the oncolytic measles virus expressing the sodium iodide symporter in iodine non-avid anaplastic thyroid cancer: a novel therapeutic agent allowing noninvasive imaging and radioiodine therapy.表达钠碘转运体的麻疹病毒在碘非亲和性间变性甲状腺癌中的临床前疗效：一种允许无创成像和放射性碘治疗的新型治疗剂。
Cancer Gene Ther. 2012 Sep;19(9):659-65. doi: 10.1038/cgt.2012.47. Epub 2012 Jul 13.
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Novel therapy for anaplastic thyroid carcinoma cells using an oncolytic vaccinia virus carrying the human sodium iodide symporter.利用携带人钠碘转运体的溶瘤痘苗病毒治疗间变性甲状腺癌细胞的新疗法。
Surgery. 2011 Dec;150(6):1040-7. doi: 10.1016/j.surg.2011.09.010.

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From the Magic Bullet to Theragnostics: Certitudes and Hypotheses, Trying to Optimize the Somatostatin Model.从神奇子弹到治疗诊断学：确信与假设，致力于优化生长抑素模型
Cancers (Basel). 2021 Jul 12;13(14):3474. doi: 10.3390/cancers13143474.
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Codon-optimized human sodium iodide symporter (opt-hNIS) as a sensitive reporter and efficient therapeutic gene.

本文引用的文献

1
Feasibility of sodium/iodide symporter gene as a new imaging reporter gene: comparison with HSV1-tk.钠/碘同向转运体基因作为新型成像报告基因的可行性：与单纯疱疹病毒1型胸苷激酶的比较
Eur J Nucl Med Mol Imaging. 2004 Mar;31(3):425-32. doi: 10.1007/s00259-003-1394-8. Epub 2003 Dec 19.
2
Therapy with 188Re-labeled radiopharmaceuticals: an overview of promising results from initial clinical trials.188铼标记放射性药物治疗：初步临床试验的有前景结果综述
Cancer Biother Radiopharm. 2003 Oct;18(5):707-17. doi: 10.1089/108497803770418256.
3
In vivo imaging and radioiodine therapy following sodium iodide symporter gene transfer in animal model of intracerebral gliomas.
密码子优化的人钠碘同向转运体（opt-hNIS）作为一种灵敏的报告基因和高效的治疗性基因。
Theranostics. 2015 Jan 1;5(1):86-96. doi: 10.7150/thno.10062. eCollection 2015.
4
Expression patterns of glucose transporter-1 gene and thyroid specific genes in human papillary thyroid carcinoma.葡萄糖转运蛋白-1基因和甲状腺特异性基因在人甲状腺乳头状癌中的表达模式
Nucl Med Mol Imaging. 2014 Jun;48(2):91-7. doi: 10.1007/s13139-013-0249-x. Epub 2014 Jan 25.
5
Sodium iodide symporter and the radioiodine treatment of thyroid carcinoma.碘化钠同向转运体与甲状腺癌的放射性碘治疗
Nucl Med Mol Imaging. 2010 Apr;44(1):4-14. doi: 10.1007/s13139-009-0016-1. Epub 2010 Feb 26.
6
The Na+/I- symporter (NIS): mechanism and medical impact.钠/碘同向转运体（NIS）：机制与医学影响。
Endocr Rev. 2014 Feb;35(1):106-49. doi: 10.1210/er.2012-1036. Epub 2013 Dec 4.
7
The sodium iodide symporter (NIS) as an imaging reporter for gene, viral, and cell-based therapies.钠碘转运体（NIS）作为基因、病毒和基于细胞的治疗的成像报告基因。
Curr Gene Ther. 2012 Feb 1;12(1):33-47. doi: 10.2174/156652312799789235.
8
A new PET probe, (18)F-tetrafluoroborate, for the sodium/iodide symporter: possible impacts on nuclear medicine.一种用于钠/碘同向转运体的新型正电子发射断层扫描（PET）探针，（18）F - 四氟硼酸盐：对核医学的潜在影响。
Eur J Nucl Med Mol Imaging. 2010 Nov;37(11):2105-7. doi: 10.1007/s00259-010-1601-3. Epub 2010 Sep 7.
9
Gene expression and gene therapy imaging.基因表达与基因治疗成像。
Eur Radiol. 2007 Feb;17(2):305-19. doi: 10.1007/s00330-006-0378-z. Epub 2006 Sep 12.
10
From the magic bullet to an effective therapy: the peptide experience.从神奇子弹到有效疗法：肽的历程
Eur J Nucl Med Mol Imaging. 2004 Oct;31(10):1393-8. doi: 10.1007/s00259-004-1661-3. Epub 2004 Sep 4.
碘化钠转运体基因转染脑胶质瘤动物模型后的体内成像及放射性碘治疗
Gene Ther. 2002 Sep;9(17):1139-45. doi: 10.1038/sj.gt.3301787.
4
Ectopic expression of the thyroperoxidase gene augments radioiodide uptake and retention mediated by the sodium iodide symporter in non-small cell lung cancer.甲状腺过氧化物酶基因的异位表达增强了非小细胞肺癌中由钠碘同向转运体介导的放射性碘摄取和潴留。
Cancer Gene Ther. 2001 Aug;8(8):612-8. doi: 10.1038/sj.cgt.7700354.
5
Imaging transcriptional regulation of p53-dependent genes with positron emission tomography in vivo.利用正电子发射断层扫描在体内成像p53依赖基因的转录调控。
Proc Natl Acad Sci U S A. 2001 Jul 31;98(16):9300-5. doi: 10.1073/pnas.161091198.
6
Relationship between expression of the sodium/iodide symporter and 131I uptake in recurrent lesions of differentiated thyroid carcinoma.钠/碘同向转运体表达与分化型甲状腺癌复发病灶中¹³¹I摄取之间的关系
Eur J Nucl Med. 2001 May;28(5):639-45.
7
Transfer of the human NaI symporter gene enhances iodide uptake in hepatoma cells.人钠碘同向转运体基因的转移增强了肝癌细胞对碘化物的摄取。
J Nucl Med. 2001 Feb;42(2):317-25.
8
Treatment of prostate cancer by radioiodine therapy after tissue-specific expression of the sodium iodide symporter.在碘化钠同向转运体组织特异性表达后通过放射性碘疗法治疗前列腺癌。
Cancer Res. 2000 Nov 15;60(22):6526-30.
9
Adenovirus-mediated transfer of the thyroid sodium/iodide symporter gene into tumors for a targeted radiotherapy.腺病毒介导的甲状腺钠/碘同向转运体基因转移至肿瘤用于靶向放射治疗。
Cancer Res. 2000 Jul 1;60(13):3484-92.
10
Molecular analysis of the sodium/iodide symporter: impact on thyroid and extrathyroid pathophysiology.钠/碘同向转运体的分子分析：对甲状腺及甲状腺外病理生理学的影响
Physiol Rev. 2000 Jul;80(3):1083-105. doi: 10.1152/physrev.2000.80.3.1083.