Massè Alessandro, Parola Pier Giorgio, Brach del Prever Elena Maria, Gallinaro Paolo
Department of Orthopaedics, Traumatology and Occupational Medicine, Clinica Ortopedica I, Università degli Studi di Torino, via Zuretti 29, 10126, Torino, Italy.
Arch Orthop Trauma Surg. 2004 Apr;124(3):203-5. doi: 10.1007/s00402-003-0624-7. Epub 2004 Feb 10.
Hydatid disease involves mainly the liver (66% of the cases) and the lungs (22%), with skeletal involvement being reported in 0.5-2.5% of cases.
Herein is reported a case of hydatidosis of the hip and pelvis with a follow-up of 25 years. The diagnosis was first done in April 1975 following the local excision of a single hydatid cyst from the ischium of a 25-year-old man complaining of increasing pain and swelling of the left thigh. Histology confirmed hydatid disease of the bone. Local excision was repeated four more times for recurrence of the hydatid cysts in the bone or soft tissues. Antiparasitic medical therapy (albendazole 10 mg/kg daily) was attempted in 1991 but suspended after 2 days due to systemic adverse effects (abdominal pain, diarrhea). The patient had a 12-year relapse-free period with complete absence of any symptoms.
Such a long symptom-free period confirms that it is not possible to consider bone hydatidosis as being completely healed without the confirmation of a long term follow-up.
包虫病主要累及肝脏(66%的病例)和肺(22%),骨骼受累报道见于0.5%-2.5%的病例。
本文报告一例髋部和骨盆包虫病病例,随访25年。1975年4月,一名25岁男性因左大腿疼痛和肿胀加剧,在对坐骨的单个包虫囊肿进行局部切除后首次确诊。组织学证实为骨包虫病。因骨或软组织中包虫囊肿复发,又进行了四次局部切除。1991年尝试抗寄生虫药物治疗(阿苯达唑每日10mg/kg),但因全身不良反应(腹痛、腹泻)在2天后停药。患者有12年无复发期,完全没有任何症状。
如此长的无症状期证实,在没有长期随访确认的情况下,不可能认为骨包虫病已完全治愈。