Boccalon H J, Candelon B J, Doll H G, Puel P F, Enjalbert A P
Cardiovasc Res. 1978 Jan;12(1):66-8. doi: 10.1093/cvr/12.1.66.
The non-invasive electromagnetic blood flowmeter described in this paper allows us to measure pulsatile flow through a limb. The limb is placed in a magnetic field and the blood flow rate induces electromagnetic forces which are detected at the skin surface with ECG electrodes (Faraday's law). A special computer technique is necessary to isolate the signal from artefacts (local ECG, BCG, EMG). In vitro calibration is performed using a circulatory model and in vivo using mongrel dogs. Its validity is assessed by comparing the results with the responses obtained from the invasive electromagnetic flowmeter. Sources of error in the measurement such as blood composition (Na+, K+), haematocrit (45% to 29%), and venous flow are reported here. The results indicate that the method is reliable, easy to utilise and offers a unique non-invasive way of measuring true pulsatile blood flow rate in humans. Various clinical applications are discussed for possible use of the device.
本文所述的无创电磁血流仪使我们能够测量通过肢体的搏动血流。将肢体置于磁场中，血流速率会感应出电磁力，该电磁力通过心电图电极在皮肤表面检测到（法拉第定律）。需要一种特殊的计算机技术来将信号与伪迹（局部心电图、体动心电图、肌电图）分离。体外校准使用循环模型进行，体内校准则使用杂种狗进行。通过将结果与侵入式电磁流量计获得的响应进行比较来评估其有效性。本文报告了测量中的误差来源，如血液成分（钠离子、钾离子）、血细胞比容（45%至29%）和静脉血流。结果表明，该方法可靠、易于使用，并且提供了一种独特的无创方式来测量人体真实的搏动血流速率。讨论了该设备可能的各种临床应用。
