Wei J
Dept. of Pediatrics, 1st Affiliated Hospital, Xi' an Medical University.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 1992 Aug;12(8):465-8, 452.
For ten years (1979-1989), 150 cases of infantile nephrotic syndrome were treated by integrated TCM and Western medicine (WM). The WM group (50 cases) was treated by conventional WM drugs (prednisone, CLB, etc) and the TCM-WM group (100 cases) was treated by the above-mentioned WM plus treatment according to Syndrome Differentiation with decoction of Chinese medicinal herbs. Wulin San, Zhenwu Tang and Zhibai Dihuang Tang were selected in treating Spleen-Qi Deficiency distressed by Dampness, both Spleen-Kidney Yang Deficiency and both Liver-Kidney Yin Deficiency Syndrome respectively. The total effective rate was 100%, and the efficacy of TCM-WM group was higher than that of WM group (P < 0.005). The efficacy of TCM-WM treatment of nephritic nephropathy was far better than that of simple nephropathy (P < 0.05). Also the efficacy of TCM-WM was superior in raising plasma albumin and reducing blood cholesterol than that of WM (P < 0.001). The cellular immunity function and plasma cortisol of TCM-WM group were significantly improved than that of WM, P < 0.01 and 0.001 respectively. The result showed that the curative effect of the TCM-WM group in treating nephrotic syndrome was much better than that of WM alone.
十年来（1979 - 1989年），采用中西医结合方法治疗小儿肾病综合征150例。西医组（50例）采用常规西药（泼尼松、环磷酰胺等）治疗，中西医结合组（100例）在上述西药治疗基础上加用中药辨证论治汤剂。分别选用五苓散、真武汤和知柏地黄丸治疗脾虚湿困证、脾肾阳虚证和肝肾阴虚证。总有效率为100%，中西医结合组疗效高于西医组（P < 0.005）。中西医结合治疗肾炎性肾病的疗效远优于单纯性肾病（P < 0.05）。中西医结合在提高血浆白蛋白和降低血胆固醇方面的疗效也优于西医（P < 0.001）。中西医结合组的细胞免疫功能和血浆皮质醇较西医组有显著改善，P值分别为< 0.01和< 0.001。结果表明，中西医结合组治疗肾病综合征的疗效明显优于单纯西医治疗。
