Raneburger J, Hohenegger M
Institute of General and Experimental Pathology, University of Vienna, Austria.
Exp Toxicol Pathol. 1992 Dec;44(7):393-7. doi: 10.1016/S0940-2993(11)80172-7.
Muscle tissue oxygen pressure (ptO2) was measured in rats employing the microwire platin electrode according to Kessler and Lübbers. In extracellular volume expansion up to 50% above the normal volume the ptO2 histograms are situated within the normal range. Increase of the interstitial space for oxygen diffusion seems to be effectively counterbalanced by increased cardiac output. In hypervolemic polyglobulia, hematocrit about 60%, four rats presented normal ptO2 levels. In one animal only the ptO2 histogram was shifted to the left (lower values); in this rat also cardiac output was considerably reduced.
根据凯斯勒和吕伯斯的方法，采用微丝铂电极在大鼠身上测量肌肉组织氧分压（ptO2）。在细胞外液量扩张至比正常量高出50%的情况下，ptO2直方图仍处于正常范围内。氧扩散的间质空间增加似乎被心输出量增加有效抵消。在血细胞比容约为60%的高血容量性红细胞增多症中，四只大鼠的ptO2水平正常。仅一只动物的ptO2直方图向左偏移（值较低）；这只大鼠的心输出量也显著降低。
