Ryder R E, Close C F, Moriarty K T, Moore K T, Hardisty C A
Diabetes Research Unit, Northern General Hospital, Sheffield, UK.
Diabet Med. 1992 Dec;9(10):893-8. doi: 10.1111/j.1464-5491.1992.tb01727.x.
In an assessment of the contributions of autonomic neuropathy and vascular disease to the aetiology of male impotence in diabetes, evidence of autonomic neuropathy was identified in 23/39 (59%) individuals complaining of impotence. Thirteen of 26 men aged < 60 years tested with an intracorporeal injection of papaverine experienced little or no response and seven had tumescence but no rigidity. Radioisotope phallography demonstrated vascular disease in six of these seven, suggesting evidence of a vascular component in 19/26 (73%). Only one patient had non-organic impotence. Overall, evidence of vascular disease alone was demonstrated in 10/26 (38%), vascular disease plus autonomic neuropathy in 9/26 (35%), and autonomic neuropathy alone in 6/26 (23%). Many diabetic men complaining of impotence appear to have a significant vascular component which renders intracorporeal papaverine treatment ineffective. We compared the performance of a vacuum constriction-band (Erecaid) and condom-type (Synergist) device in 10 randomly selected men from this group. The devices, provided in random order for 5 months each, were assessed by questionnaire and interview of both the patient and partner. Two couples defaulted and another could use neither device. Although erectile capacity could be restored in the remainder, subsequent intercourse was only deemed satisfactory to both partners in five couples, who unanimously preferred the constriction-band device. In treatment with vacuum devices the constriction-band type seems to be the device of choice; the condom type should probably be reserved for those unable to use the constriction-band type.
在一项关于自主神经病变和血管疾病对糖尿病男性阳痿病因学贡献的评估中,在39名主诉阳痿的个体中,有23名(59%)被发现存在自主神经病变的证据。26名年龄<60岁的男性接受阴茎海绵体内注射罂粟碱测试,其中13名几乎没有反应或完全无反应,7名有肿胀但无硬度。放射性同位素阴茎造影显示这7名中的6名存在血管疾病,提示26名中有19名(73%)存在血管因素。只有1例患者为非器质性阳痿。总体而言,仅存在血管疾病证据的有26名中的10名(38%),血管疾病加自主神经病变的有26名中的9名(35%),仅存在自主神经病变的有26名中的6名(23%)。许多主诉阳痿的糖尿病男性似乎有显著的血管因素,这使得阴茎海绵体内注射罂粟碱治疗无效。我们比较了真空缩窄环(Erecaid)和避孕套型(Synergist)装置在从该组中随机选取的10名男性中的使用情况。这些装置以随机顺序提供,每种使用5个月,通过对患者及其伴侣进行问卷调查和访谈来评估。两对夫妇未继续使用,另有一对夫妇两种装置都无法使用。尽管其余患者的勃起功能得以恢复,但只有5对夫妇的后续性交被双方认为满意,他们一致更喜欢缩窄环装置。在真空装置治疗中,缩窄环型似乎是首选装置;避孕套型可能应保留给无法使用缩窄环型的患者。