Chaudhuri A, Wiles P
Diabetes Centre, North Manchester Healthcare NHS Trust, Crumpsall, England.
Drugs. 1995 Apr;49(4):548-54. doi: 10.2165/00003495-199549040-00005.
Erectile failure, although a common problem in male diabetic patients, is one of the most neglected complications of diabetes. The availability of drugs like alprostadil (prostaglandin E1; PGE1) and papaverine for intracavernosal injection and the development of vacuum tumescence devices, while making therapy simple, have also reduced the necessity for specialised investigations. In the past 10 years, alprostadil has been shown to be the safest and the most effective of the intracavernosal self-injection treatments of erectile dysfunction. Vacuum tumescence devices are an acceptable noninvasive alternative in those who fail to achieve a satisfactory response to self-injection. Surgical techniques are being improved every day, and revascularisation procedures and prosthetic implants are available to couples in specialised centres. At present, systemic drug therapy has been largely ineffective for treatment in diabetic patients but progress is being made in this field. Whatever the option, involvement of the partner in decision making is of major importance for the treatment to be successful, and psychosexual counselling is a useful adjunct to medical or surgical therapy.
勃起功能障碍虽然是男性糖尿病患者的常见问题，但却是糖尿病最易被忽视的并发症之一。像前列地尔（前列腺素E1；PGE1）和罂粟碱这类用于海绵体内注射的药物的出现，以及真空勃起装置的研发，在使治疗变得简单的同时，也降低了进行专门检查的必要性。在过去10年里，前列地尔已被证明是治疗勃起功能障碍的海绵体内自我注射疗法中最安全、最有效的药物。对于那些对自我注射未能取得满意反应的患者，真空勃起装置是一种可接受的非侵入性替代方法。外科技术日益改进，在专业中心，血管重建手术和假体植入可供夫妇选择。目前，全身药物治疗在糖尿病患者的治疗中大多无效，但该领域正在取得进展。无论选择何种治疗方式，伴侣参与决策对于治疗成功至关重要，性心理咨询是药物或手术治疗的有益辅助手段。
