Mori M, Kakeji Y, Adachi Y, Korenaga D, Sugimachi K
Second Department of Surgery, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Eur J Surg Oncol. 1992 Dec;18(6):632-5.
A 69-year-old Japanese woman with early carcinoma of the stomach was treated. Postoperative pathological examination of the resected stomach disclosed a widely spreading early carcinoma and two concomitant submucosal lesions which were histologically compatible with inflammatory fibroid polyp (IFP). Neither IFP showed a polypoid appearance: instead they had a down-growth pattern. The covering mucosa was replaced by gastric carcinoma cells. The IFPs were located mainly in the submucosa, but reached invasively to the subserosa through the proper muscular layer. The boundaries of the lesions were well demarcated in the submucosa but poorly demarcated in the subserosa. This case is very rare because the two IFPs showed a down-growth pattern and were concomitant with early gastric carcinoma.
一名69岁的日本女性因早期胃癌接受了治疗。对切除的胃进行术后病理检查发现,存在广泛扩散的早期癌以及两个与之并存的黏膜下病变,组织学上与炎性纤维性息肉(IFP)相符。两个IFP均未表现出息肉样外观,而是呈向下生长模式。覆盖的黏膜被胃癌细胞取代。IFP主要位于黏膜下层,但通过固有肌层浸润至浆膜下层。病变在黏膜下层边界清晰,但在浆膜下层边界不清。该病例非常罕见,因为这两个IFP呈向下生长模式且与早期胃癌并存。