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用于兔输卵管再吻合的纤维蛋白胶:粘连与生育能力

Fibrin glue for reanastomosis of the fallopian tube in the rabbit: adhesions and fertility.

作者信息

Gauwerky J F, Klose R P, Vierneisel P, Bastert G

机构信息

University of Heidelberg, FRG.

出版信息

Hum Reprod. 1992 Oct;7(9):1274-7. doi: 10.1093/oxfordjournals.humrep.a137841.

Abstract

Fertility and adhesions were examined in 41 rabbits in three treatment groups following the construction of microsurgical anastomoses with fibrin glue and by conventional suturing techniques. The three types of treatment were: isthmic anastomoses without resection, ampullary anastomoses, isthmic anastomoses following resection of oviduct segments. There were no significant differences between the two methods of performing the anastomoses in any of the three groups with respect to number of ovulations, number of implantations, nidation index, and pregnancy rate. The extent of the formation of adhesions was also no different between the two types of anastomosis construction. From the functional point of view, fibrin glueing of the tubes can be considered as good as microsurgical suturing. Another study is planned to examine whether this is also true from the morphological viewpoint. It must be remarked that fibrin glueing does not appear to be suitable for anastomoses in which a lumen-adjusting technique is needed or for deep tubocornual or intramural anastomoses.

摘要

在通过纤维蛋白胶和传统缝合技术构建显微外科吻合术后,对三个治疗组的41只兔子的生育能力和粘连情况进行了检查。三种治疗类型分别为:未切除的峡部吻合术、壶腹部吻合术、输卵管段切除后的峡部吻合术。在排卵数量、着床数量、着床指数和妊娠率方面,三组中两种吻合方法之间均无显著差异。两种吻合构建类型之间的粘连形成程度也没有差异。从功能角度来看,用纤维蛋白胶粘合输卵管可被认为与显微外科缝合一样好。计划进行另一项研究,以检查从形态学角度来看是否也是如此。必须指出的是,纤维蛋白胶似乎不适用于需要管腔调整技术的吻合术,也不适用于深部输卵管子宫角或壁内吻合术。

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