自体纤维蛋白粘合剂在实验性输卵管吻合术中的应用
Autologous fibrin adhesive in experimental tubal anastomosis.
作者信息
Rajaram S, Rusia U, Agarwal S, Agarwal N
机构信息
Department of Obstetrics & Gynaecology, University College of Medical Sciences, Delhi, India.
出版信息
Int J Fertil Menopausal Stud. 1996 Sep-Oct;41(5):458-61.
OBJECTIVE
To evaluate autologous fibrin in rabbit oviduct anastomosis versus 7-0 vikryl, a conventional suture material used in tubal anastomosis.
METHODS
Thrombin was added to the autologous fibrinogen at the site of anastomosis to obtain a tissue adhesive. The anastomotic time, pregnancy rate, and litter size were evaluated. Three months later, a relaparotomy was done to evaluate patency and degree of adhesions, and a tubal biopsy was taken from the site of anastomosis.
RESULTS
Analysis of results showed a statistically significant (P < .001) shortened anastomotic time and superior histopathological union in the tissue adhesive group. Patency rate, pregnancy rate, and degree of adhesions were comparable in both groups.
目的
评估自体纤维蛋白在兔输卵管吻合术中与7-0薇乔（一种用于输卵管吻合术的传统缝合材料）相比的效果。
方法
在吻合部位将凝血酶添加到自体纤维蛋白原中以获得组织粘合剂。评估吻合时间、妊娠率和产仔数。三个月后，再次剖腹手术以评估通畅性和粘连程度，并从吻合部位取输卵管活检组织。
结果
结果分析显示，组织粘合剂组的吻合时间在统计学上显著缩短（P <.001），组织病理学愈合情况更好。两组的通畅率、妊娠率和粘连程度相当。
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