Mintz G, Galindo L F, Fernández-Diez J, Jiménez F J, Robles-Saavedra E, Enríquez-Casillas R D
J Rheumatol. 1978 Spring;5(1):39-50.
Acute massive pulmonary hemorrhage is described as part of the clinical picture of SLE. Seven patients had sudden onset of high fever, dyspnea, tachycardia, and cough with blood-tinged sputum that within hours progressed to massive hemoptysis and death. There were no vasculitis or other inflammatory lung changes found at autopsy. Only one of the seven reported cases survived when treated with 2 g of intravenous hydrocortisone daily. The mechanism of this pulmonary bleeding is unknown but seems to be an immune complex mediated phenomenon.
急性大量肺出血被描述为系统性红斑狼疮临床症状的一部分。7名患者突然出现高热、呼吸困难、心动过速以及伴有血痰的咳嗽，数小时内病情进展为大量咯血并死亡。尸检未发现血管炎或其他肺部炎症改变。7例报告病例中仅有1例在每日静脉注射2克氢化可的松治疗后存活。这种肺出血的机制尚不清楚，但似乎是一种免疫复合物介导的现象。
