Minamikawa K, Wada H, Ohiwa M, Kaneko T, Tsukada T, Kageyama S, Kobayashi T, Tomeoku M, Katou M, Minami N
2nd Department of Internal Medicine, Mie University School of Medicine.
Rinsho Ketsueki. 1992 Dec;33(12):1797-801.
Plasma Interleukin-6 (IL-6) level was measured in 60 patients with disseminated intravascular coagulation (DIC). Plasma IL-6 level was high in patients with DIC, and was particularly high in patients with multiple organ failure (MOF) or poor prognosis. Plasma IL-6 level correlated positively with C-reactive protein in patients without DIC, but not in those with DIC. The increased plasma IL-6 level observed in DIC patients suggests that activation of the immune system is involved in the progression of DIC and in the pathology of organ failure.
对60例弥散性血管内凝血（DIC）患者测定了血浆白细胞介素-6（IL-6）水平。DIC患者血浆IL-6水平较高，在多器官功能衰竭（MOF）或预后不良的患者中尤其高。在无DIC的患者中，血浆IL-6水平与C反应蛋白呈正相关，但在DIC患者中并非如此。DIC患者中观察到的血浆IL-6水平升高表明，免疫系统的激活参与了DIC的进展及器官衰竭的病理过程。
