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[1991年蒂罗尔州血培养阳性中的病原体谱]

[The spectrum of pathogens in positive blood cultures--Tyrol 1991].

作者信息

Allerberger F, Schneidinger M, Neher C, Brezinka C, Guggenbichler J P, Dierich M P

机构信息

Bundesstaatlichen bakteriologisch-serologischen Untersuchungsanstalt Innsbruck.

出版信息

Wien Med Wochenschr. 1992;142(17):385-9.

PMID:1481545
Abstract

In a recent study by the Centers for Disease Control (CDC) it was noted that there had been a resurgence of Gram-positive bacteremia together with an increase in fungemia. This reported trend is confirmed by data from the Austrian Tirol. In 1991 1,750 out of 13,679 specimens (12.8%) yielded bacterial or fungal growth, accounting for 1,248 cases of "bacteremia"; no decision was made about the clinical significance of the culture isolates. We consider laboratory reports of blood isolates to be fairly well suited to reflect the frequency of the various bacterial and fungal pathogens. The most common organisms were coagulase-negative staphylococci (41%). The proportion of Staphylococcus aureus (17%), E. coli (4%), Klebsiella-Enterobacter (4%), Pseudomonas (5%) and Candida (3%) corresponded well with the situation in the USA and the UK. Remarkably, anaerobes accounted for only 0.3%, possibly due to our use of a "single bottle"--blood-culture system. Various fastidious organisms, including Brucella melitensis and Haemophilus aphrophilus, were detected by this blood-culture system. Also 15 Haemophilus influenzae-strains, nontyphoidal salmonellae (9 strains), and meningococci (7 strains) were isolated. These data show that the microbiologic features of blood-cultured seen in Austrian Tyrol are broadly similar to those in the UK and North America.

摘要

美国疾病控制中心(CDC)最近的一项研究指出,革兰氏阳性菌血症有所复发,同时真菌血症也有所增加。奥地利蒂罗尔的数据证实了这一报告趋势。1991年,13679份标本中有1750份(12.8%)出现细菌或真菌生长,确诊为1248例“菌血症”;未对培养分离株的临床意义做出判定。我们认为血液分离株的实验室报告相当适合反映各种细菌和真菌病原体的出现频率。最常见的病原体是凝固酶阴性葡萄球菌(41%)。金黄色葡萄球菌(17%)、大肠杆菌(4%)、克雷伯菌-肠杆菌(4%)、假单胞菌(5%)和念珠菌(3%)的比例与美国和英国的情况相当。值得注意的是,厌氧菌仅占0.3%,这可能是由于我们使用了“单瓶”血液培养系统。通过该血液培养系统检测到了各种苛养菌,包括羊布鲁氏菌和嗜沫嗜血杆菌。还分离出15株流感嗜血杆菌、非伤寒沙门氏菌(9株)和脑膜炎球菌(7株)。这些数据表明,奥地利蒂罗尔血液培养的微生物学特征与英国和北美的大致相似。

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