Siché J P, de Gaudemaris R, Riachi M, Benhamou P Y, Tremel F, Halimi S, Pitiot M, Mallion J M
Service de médecine interne et cardiologie, CHU de Grenoble.
Arch Mal Coeur Vaiss. 1992 Aug;85(8):1145-8.
examination of an automated exploration of autonomic neuropathy using the Ewing score and evaluation of sympatho-vagal tone.
continuous non-invasive collection of blood pressure (BP) data by means of Finapress fingerprobe. The signal was analysed after digitization at 500Hz, sampled and computerised. Values of systolic BP (SBP), diastolic BP (DBP) and heart rate (HR) are analysed by Anapres (Notochord).
the pressure monitor is placed on the finger and the reading calibrated to the BP value recorded by auscultatory method on the contralateral arm to give a gap of less than 10 mmHg. BP and HR response to five different manoeuvres are recorded, namely: at rest over 7 minutes, after lying decubitus for 15 minutes; on rising suddenly over 3 seconds, and then over 9 minutes standing still; during 2 respiratory manoeuvres (a) deep breathing over 6 cycles per minute, (b) Valsalva pressure at 40 mmHg sustained over 20 seconds; isometric exercise with sustained handgrip at 30% maximal force sustained over 3 minutes.
a dedicated computer programme displays in graphic form BP and HR over each manoeuvre and allows the operator to locate the exact cut-off of normality for each test of the Ewing score and also measure the balance of sympatho-vagal tone by Fourier transformation of the interval data of HR or BP peaks.
this approach allows evaluation of autonomic function and sympatho-vagal tone by means of 40 minutes of clinical testing and two minutes of automated analysis. This approach seems useful in the assessment of the autonomic nervous system in diabetes.
使用尤因评分法自动探索自主神经病变并评估交感 - 迷走神经张力。
通过Finapress手指探头连续无创收集血压（BP）数据。信号在以500Hz数字化后进行分析、采样并计算机化处理。收缩压（SBP）、舒张压（DBP）和心率（HR）值由Anapres（Notochord）进行分析。
将压力监测器置于手指上，并将读数校准至对侧手臂听诊法记录的血压值，使差值小于10mmHg。记录血压和心率对五种不同动作的反应，即：静息7分钟；卧位15分钟后；突然起立3秒，然后站立静止9分钟；进行两次呼吸动作（a）每分钟6个周期的深呼吸，（b）40mmHg的瓦尔萨尔瓦压力持续20秒；以最大力量的30%持续握力3分钟进行等长运动。
一个专门的计算机程序以图形形式显示每个动作过程中的血压和心率，并允许操作员确定尤因评分法每项测试的正常精确临界值，还可通过对心率或血压峰值的间期数据进行傅里叶变换来测量交感 - 迷走神经张力的平衡。
这种方法通过40分钟的临床测试和两分钟的自动分析来评估自主神经功能和交感 - 迷走神经张力。这种方法在评估糖尿病患者的自主神经系统方面似乎很有用。
