Chau N P, Chanudet X, Sevin E, Bauduceau B, Gautier D, Larroque P
Unité de recherches biomathématiques et biostatistiques, INSERM U263, Université Paris VII.
Arch Mal Coeur Vaiss. 1992 Aug;85(8):1181-4.
We applied a simplified version of the method suggested by Sugihara-May (Nature 1990: 344: 734-41) to study the control of heart rate (HR) in subjects with diabetes mellitus. The method aims to predict the future of an observation, if a series of observations on the same phenomenon is available. The method quantifies the fact that the series is predictable more or less longtime in the future. A random series is only shortly predictable in the future. HR and blood pressure were measured from beat to beat (by the Finapres system) for about 0.5 hours in 11 subjects with diabetes mellitus and normal blood pressure (group D) and in 10 controls subjects (group N). The subjects were sitting in a temperature-controlled quiet room, isolated from all external stimuli. The 2 groups were matched for age, and had the same weight and height. No difference was observed in mean-value and standard deviation (SD) of BP and HR between the 2 groups. Groups N/D: SBP = 112 +/- 11/123 +/- 11 mmHg, NS; DBP = 64 +/- 9/67 +/- 12 mmHg, NS; HR = 70 +/- 10/69 +/- 7 b/min, NS. Standard deviation of PAS = 5.5 +/- 1.6/5.7 +/- 1.9 mmHg, NS and SD of DBP = 3.5 +/- 0.9/3.4 +/- 1.2 mmHg, NS. The SD of HR (3.0 +/- 0.5/2.3 +/- 1.0 b/min in groups N/D) was somewhat lower in diabetics than in control subjects but the difference was not significant.(ABSTRACT TRUNCATED AT 250 WORDS)
我们应用了杉原-梅(《自然》1990年:344卷:734 - 41页)提出方法的简化版本,来研究糖尿病患者心率(HR)的控制情况。该方法旨在预测一个观测值的未来情况,前提是有关于同一现象的一系列观测值。此方法量化了这样一个事实,即该序列在未来或多或少的长时间内是可预测的。随机序列在未来只能短期预测。在11名血压正常的糖尿病患者(D组)和10名对照受试者(N组)中,使用连续无创动脉压监测系统逐搏测量心率和血压约0.5小时。受试者坐在温度受控的安静房间里,与所有外部刺激隔离。两组在年龄上相匹配,体重和身高相同。两组之间收缩压、舒张压和心率的平均值及标准差均无差异。N/D组:收缩压 = 112 ± 11/123 ± 11 mmHg,无显著差异;舒张压 = 64 ± 9/67 ± 12 mmHg,无显著差异;心率 = 70 ± 10/69 ± 7次/分钟,无显著差异。肺动脉收缩压标准差 = 5.5 ± 1.6/5.7 ± 1.9 mmHg,无显著差异,舒张压标准差 = 3.5 ± 0.9/3.4 ± 1.2 mmHg,无显著差异。糖尿病患者心率的标准差(N/D组为3.0 ± 0.5/2.3 ± 1.0次/分钟)略低于对照受试者,但差异不显著。(摘要截选至250字)