Sopelana P, Débora M, López-Calvo S, García-Alvarez J C, Polo C
Unidad de Desintoxicación de Drogodependientes, Hospital Psiquiátrico, Madrid.
Arch Neurobiol (Madr). 1992 Sep-Oct;55(5):228-34.
The early organic mental disorder, caused by the human immunodeficiency virus type 1 (HIV) in the drug dependents (DD), if it is not taken into account, can disturb the diagnosis of the neuropsychiatric and the toxic disorders. The authors attempt to outline, with several neuropsychological tests (visuo-perceptual, memory, attention) and with the physical and neurologic exploration, if cognitive abnormalities are present in two groups of DD after detoxification period. The first group is infected by the HIV (n: 48), and the second one is not (n: 33). Differences can be found only in the Bender visuo-perceptual test, which are not justified by the divergences found between the groups about the drug dependence history and the present drug of abuse intake. The importance of the early diagnosis of these abnormalities is argued in order to get a suitable treatment of the possible neuropsychiatric complications in the DD development, and restrain the extent of the cognitive damage by HIV infection.
在药物依赖者中，由1型人类免疫缺陷病毒（HIV）引起的早期器质性精神障碍，如果不加以考虑，可能会干扰神经精神疾病和中毒性疾病的诊断。作者试图通过多项神经心理学测试（视觉感知、记忆、注意力）以及体格和神经学检查，来勾勒戒毒期后两组药物依赖者中是否存在认知异常。第一组感染了HIV（n = 48），第二组未感染（n = 33）。仅在本德尔视觉感知测试中发现了差异，而两组在药物依赖史和当前滥用药物摄入方面的差异并不能解释这些差异。文中强调了早期诊断这些异常的重要性，以便在药物依赖者病情发展过程中对可能出现的神经精神并发症进行适当治疗，并限制HIV感染造成的认知损害程度。
