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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

J Gen Physiol. 1951 Jan;34(3):359-72. doi: 10.1085/jgp.34.3.359.

The anomalous course of the curves relating K loss to time in systems containing human red cells in isotonic NaCl, and particularly the high positions of the asymptotes to which the curves apparently proceed, are due to the population of red cells consisting of at least two components, one of which loses K more readily than the other. 2. Since large K-Na exchanges can occur between red cells and an isotonic suspension medium without there being large volume changes, a restatement of the "dual mechanism of hemolysis" hypothesis, which takes account of the cell's being slowly permeable to cations, is required. If some approximations of minor consequence are allowed, the hypothesis can be restated in a quantitatively satisfactory way. 3. The general features of K-Na exchanges, including prolytic exchanges are summarized.

在含有等渗氯化钠溶液中的人体红细胞系统中，钾流失与时间关系曲线的异常走向，尤其是曲线明显趋近的渐近线的高位，是由于红细胞群体至少由两个组分组成，其中一个组分比另一个组分更容易丢失钾。2. 由于红细胞与等渗悬浮介质之间可发生大量的钾 - 钠交换而无大的体积变化，因此需要重新阐述“溶血双机制”假说，该假说考虑到细胞对阳离子的缓慢渗透性。如果允许一些次要的近似处理，该假说可以以定量上令人满意的方式重新表述。3. 总结了钾 - 钠交换的一般特征，包括水解性交换。

J Gen Physiol. 1951 Jan;34(3):359-72. doi: 10.1085/jgp.34.3.359.

The anomalous course of the curves relating K loss to time in systems containing human red cells in isotonic NaCl, and particularly the high positions of the asymptotes to which the curves apparently proceed, are due to the population of red cells consisting of at least two components, one of which loses K more readily than the other. 2. Since large K-Na exchanges can occur between red cells and an isotonic suspension medium without there being large volume changes, a restatement of the "dual mechanism of hemolysis" hypothesis, which takes account of the cell's being slowly permeable to cations, is required. If some approximations of minor consequence are allowed, the hypothesis can be restated in a quantitatively satisfactory way. 3. The general features of K-Na exchanges, including prolytic exchanges are summarized.

在含有等渗氯化钠溶液中的人体红细胞系统中，钾流失与时间关系曲线的异常走向，尤其是曲线明显趋近的渐近线的高位，是由于红细胞群体至少由两个组分组成，其中一个组分比另一个组分更容易丢失钾。2. 由于红细胞与等渗悬浮介质之间可发生大量的钾 - 钠交换而无大的体积变化，因此需要重新阐述“溶血双机制”假说，该假说考虑到细胞对阳离子的缓慢渗透性。如果允许一些次要的近似处理，该假说可以以定量上令人满意的方式重新表述。3. 总结了钾 - 钠交换的一般特征，包括水解性交换。