Perevoshchikov A G
Arkh Patol. 1978;40(2):33-9.
Electron-histochemical study of phosphohydrolases (ATPase, acid and alkaline phosphatases) in cells of the normal gastric mucosa, duodenal mucosa and gastric adenocarcinoma of man was carried out. In cancer cells retaining to a certain extent the ultrastructural features of the chief cells, parietal cells of enterocytes, the distribution of the product of reaction for ATPase and acid phosphatase in nucleoli, endoplasmic reticulum membranes, intracellular cannaliculi, plasmalemma, mitochondria, the distribution of the product of reaction for ATPase and acid phosphatase in nucleoli, tural features of enterocytes, no activity of alkaline phosphatase could be demonstrated in membranes of the villi of the striated border. Alongside with the retention or disappearance of electron-histochemical features, some of them may be enhanced. Thus, the activity of acid phosphatase was increased in lysosomes of cancer cells (of the type of chief cells). So, in cancer cells of adenocarcinoma the structure-functional rearrangement going in different directions is observed in addition to the process of simplification and unification.
对人正常胃黏膜、十二指肠黏膜及胃腺癌细胞中的磷酸水解酶（ATP酶、酸性和碱性磷酸酶）进行了电子组织化学研究。在一定程度上保留主细胞、肠上皮细胞壁细胞超微结构特征的癌细胞中，ATP酶和酸性磷酸酶反应产物在核仁、内质网膜、细胞内小管、质膜、线粒体中的分布，肠上皮细胞的结构特征，在纹状缘绒毛膜中未显示碱性磷酸酶活性。除了电子组织化学特征的保留或消失外，其中一些特征可能会增强。因此，癌细胞（主细胞类型）的溶酶体中酸性磷酸酶活性增加。所以，在腺癌癌细胞中，除了简化和统一过程外，还观察到朝着不同方向进行的结构-功能重排。
