Dobrovol'skiĭ S R, Grigor'eva S P, Parshin V D
Grud Serdechnososudistaia Khir. 1992(9-10):45-52.
Repeated uni- and bilateral resections of the lungs conducted from 1963 to 01.01.91 at the Department of Surgery of the Lungs and Mediastinum of the National Research Center of Surgery, USSR AMS for primary multiple carcinoma (13 patients) and metastatic lesions (32 patients) accounted for 1.3% of all operations in lung carcinoma. Such interventions are more justified in differentiated forms of primary multiple carcinoma and in solitary and occasional metastases of malignant tumors of various localization to the lungs. Morphological signs are the main differential diagnostic criteria of primary multiple carcinoma and intrapulmonary metastases. The main principle of surgical treatment of patients with primary multiple carcinoma and metastatic involvement of the lungs is an economical character of the operation with maximally admissible, from the oncological standpoint, preservation of functionally valuable pulmonary tissue. The combined method of treatment (operation + drug antineoplastic therapy) should take the leading place in the management of patients with intrapulmonary metastases of malignant tumors.
1963年至1991年1月1日期间,苏联医学科学院国家外科研究中心肺与纵隔外科对原发性多发性癌(13例)和转移性病变(32例)进行了多次单侧和双侧肺切除术,占肺癌所有手术的1.3%。这种干预措施在原发性多发性癌的分化型以及各种部位恶性肿瘤的孤立性和偶然性肺转移中更具合理性。形态学特征是原发性多发性癌和肺内转移的主要鉴别诊断标准。原发性多发性癌和肺转移患者手术治疗的主要原则是手术的经济性,从肿瘤学角度看,要最大程度地保留功能上有价值的肺组织。联合治疗方法(手术+抗肿瘤药物治疗)应在恶性肿瘤肺内转移患者的治疗中占据主导地位。