KALTER S S, SMOLIN H J, McELHANEY J M, TEPPERMAN J
J Exp Med. 1951 Jun;93(6):529-38. doi: 10.1084/jem.93.6.529.
Treatment with testosterone increases proliferation of influenza virus as well as protein anabolism. A relative lack of testosterone caused by castration is associated with a diminished rate of virus growth. When protein catabolism is increased by ACTH or cortisone, the rate of virus proliferation decreases. These results suggest the existence of a correlation between alterations of protein metabolism and virus proliferation.
睾酮治疗可增加流感病毒的增殖以及蛋白质合成代谢。去势导致的睾酮相对缺乏与病毒生长速率降低有关。当促肾上腺皮质激素或可的松使蛋白质分解代谢增加时,病毒增殖速率下降。这些结果表明蛋白质代谢改变与病毒增殖之间存在相关性。