Rothschild B M, Woods R J, Rothschild C
Arthritis Center of Northeast Ohio, Youngstown 44512.
Clin Exp Rheumatol. 1992 Nov-Dec;10(6):557-64.
The osseous appearance, skeletal distribution, and distinguishing features of calcium pyrophosphate deposition disease (CPPD) were delineated in a population of 2906 contemporary defleshed skeletons. The limitations of routine x-ray and clinical examination were transcended in this study of defleshed bones. The nature of the disease was clearly identified and preconceived notions (based on the "shades of black and white" of the conventional x-ray technique) were examined on the basis of the actual osseous impact. Epidemiologic assessment of this disease allowed it to be distinguished from rheumatoid and other erosive forms of arthritis. Analysis of the "pseudo-rheumatoid" subgroup of CPPD provided clear criteria for distinguishing the disease from rheumatoid arthritis. Characterization of the nature and epidemiology of osseous alterations in a contemporary skeletal population permitted the development of a standard for recognition of CPPD in skeletal populations and for clarification of the nature of associated pseudo-erosions.
在2906具当代剔肉骨骼组成的样本中，对焦磷酸钙沉积病（CPPD）的骨质表现、骨骼分布及特征进行了描述。在这项对剔肉骨骼的研究中，超越了常规X光检查和临床检查的局限性。该疾病的本质得以明确识别，并基于实际骨质影响对（基于传统X光技术的“黑白影像”）先入之见进行了审视。对该疾病的流行病学评估使其得以与类风湿性关节炎及其他侵蚀性关节炎形式相区分。对CPPD“类类风湿”亚组的分析为区分该疾病与类风湿性关节炎提供了明确标准。对当代骨骼样本中骨质改变的本质及流行病学特征进行描述，有助于制定在骨骼样本中识别CPPD以及阐明相关假性侵蚀本质的标准。
