Chambers I R, Choksey M S, Clark A, Green A, Jenkins A, Mendelow A D
Regional Medical Physics Department, Newcastle General Hospital, Newcastle upon Tyne, UK.
Clin Phys Physiol Meas. 1992 Nov;13(4):311-21. doi: 10.1088/0143-0815/13/4/002.
Thermal clearance has been used as a measure of tissue blood flow for over 60 years. We have developed a probe which can be used to monitor cerebral cortical thermal clearance in patients suffering from acute neurosurgical disorders. Despite its limitations of size, invasiveness, small sample volume, and difficult quantification it has proved a reliable method, showing a good correlation between measured thermal clearance and the onset of clinical signs of ischaemia.
热清除率作为组织血流的一种测量方法已使用了60多年。我们研发了一种探头，可用于监测患有急性神经外科疾病患者的大脑皮质热清除率。尽管它存在尺寸受限、具有侵入性、样本量小以及量化困难等局限性，但它已被证明是一种可靠的方法，所测得的热清除率与缺血临床体征的出现之间显示出良好的相关性。
