Rett K
Institut für Diabetesforschung, Krankenhaus München-Schwabing.
Fortschr Med. 1992 Dec 10;110(34):642-4.
Essential hypertension in patients with the metabolic syndrome is regularly associated with other metabolic disorders. Thus, most hypertensives are overweight and have a glucose intolerance, while many have concomitant hyperproteinemia and dyslipoproteinemia. Up until fairly recently, it was not known that so-called insulin resistance is a common denominator both of metabolic risk factors and hypertension. In recent years, our knowledge about insulin resistance has spawned an equally convincing and fascinating multidimensional concept which reveals and plausibly explains complex relationships between metabolism, hypertension and the coronary risk.
代谢综合征患者的原发性高血压常与其他代谢紊乱相关。因此，大多数高血压患者超重且存在糖耐量异常，同时许多患者伴有高蛋白血症和血脂蛋白异常血症。直到最近，人们才知道所谓的胰岛素抵抗是代谢危险因素和高血压的共同特征。近年来，我们对胰岛素抵抗的认识催生了一个同样令人信服且引人入胜的多维度概念，该概念揭示并合理地解释了代谢、高血压和冠心病风险之间的复杂关系。
