Suppr超能文献

[胸主动脉急性和亚急性夹层:磁共振断层扫描的诊断重要性]

[Acute and subacute dissection of the thoracic aorta: diagnostic importance of magnetic resonance tomography].

作者信息

Nienaber C A, von Kodolitsch Y, Spielmann R P

机构信息

Abteilung für Kardiologie und Angiologie, Universitätskrankenhauses Hamburg-Eppendorf.

出版信息

Herz. 1992 Dec;17(6):338-47.

PMID:1483623
Abstract

The purpose of this study was to retrospectively assess the reliability of ECG-triggered magnetic resonance imaging (MRI) for the diagnosis of acute and subacute thoracic aortic dissection and associated clinical epiphenomena. 67 patients were subjected to MRI; the diagnostic results were compared with morphological standards. 25 patients had type A, 12 patients type B dissection. In 30 cases a dissection was excluded. 17 patients with aortic dissection had acute onset of symptoms, 10 patients had subacute onset of symptoms. 17 patients revealed thrombosis of the false lumen, which was found in the descending aorta in 59% of the cases. Aortic regurgitation and pericardial effusion was most often associated with type A dissection (Table 1). Three patients were studied while on mechanical ventilation. Scan time for MRI ranged from 15 to 71 minutes with an average of 46 +/- 18 minutes. In this series no deleterious events were encountered related to MRI diagnostics. In contrast to previously published data using other noninvasive techniques the sensitivity of MRI was 100% for detecting a dissection in the ascending segment of the thoracic aorta. Moreover, the specificity of MRI for a dissection was 100% and thus higher than previously published data using transesophageal echocardiography. Sensitivity and specificity for detection and correct classification of type B dissection was 100% and 100% respectively (Table 2). In addition, MRI proved to be sensitive in detecting the formation of thrombus material in the false lumen of the ascending aorta (92%), the aortic arch (100%) and the descending segment (88%). Specificity for exclusion of suspected thrombus material even proved to be slightly higher with 100% in the ascending and descending aorta and 96.1% in the aortic arch (Table 3). The site of entry to a dissection was detected in 78%, with a sensitivity of 76% in the ascending and 92% in the descending aorta. The involvement of side branches in the dissecting process was identified in 60%. There were no false positive findings concerning side branch involvement. Aortic regurgitation and pericardial effusion were detected in 100% and 100%, respectively (Tables 1 and 2). MRI performed even in acute cases proved to be a atraumatic, safe and highly sensitive method to identify and classify acute and subacute dissections of the entire thoracic aorta. Limited patient access was not associated with an increased risk and mechanical ventilation did not interfere with MRI. These results may establish MRI as a valid and promising noninvasive technique to establish the diagnosis in patients with thoracic aortic dissection.(ABSTRACT TRUNCATED AT 400 WORDS)

摘要

本研究的目的是回顾性评估心电图触发的磁共振成像(MRI)用于诊断急性和亚急性胸主动脉夹层及相关临床附带现象的可靠性。67例患者接受了MRI检查;将诊断结果与形态学标准进行比较。25例为A型夹层,12例为B型夹层。30例排除夹层。17例主动脉夹层患者症状急性发作,10例症状亚急性发作。17例患者显示假腔血栓形成,其中59%见于降主动脉。主动脉瓣关闭不全和心包积液最常与A型夹层相关(表1)。3例患者在机械通气时接受研究。MRI扫描时间为15至71分钟,平均46±18分钟。在本系列研究中,未遇到与MRI诊断相关的有害事件。与先前使用其他非侵入性技术发表的数据相比,MRI检测胸主动脉升段夹层的敏感性为100%。此外,MRI诊断夹层的特异性为100%,因此高于先前使用经食管超声心动图发表的数据。检测和正确分类B型夹层的敏感性和特异性分别为100%和100%(表2)。此外,MRI在检测升主动脉(92%)、主动脉弓(100%)和降段(88%)假腔内血栓形成方面被证明是敏感的。排除可疑血栓形成的特异性在升主动脉和降主动脉甚至略高,分别为100%,在主动脉弓为96.1%(表3)。夹层入口部位的检测率为78%,在升主动脉的敏感性为76%,在降主动脉为92%。60%的患者识别出夹层过程中分支血管受累情况。关于分支血管受累情况没有假阳性发现。主动脉瓣关闭不全和心包积液的检测率分别为100%和100%(表1和表2)。即使在急性病例中进行的MRI检查也被证明是一种无创、安全且高度敏感的方法,可用于识别和分类整个胸主动脉的急性和亚急性夹层。有限的患者入路并未增加风险,机械通气也未干扰MRI检查。这些结果可能使MRI成为诊断胸主动脉夹层患者的一种有效且有前景的非侵入性技术。(摘要截选至400字)

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验