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[胸主动脉夹层的外科治疗]

[Surgical therapy of thoracic aortic dissection].

作者信息

Hake U, Oelert H

机构信息

Klinik und Poliklinik für Herz-, Thorax- und Gefässchirurgie, Johannes-Gutenberg-Universität Mainz.

出版信息

Herz. 1992 Dec;17(6):357-76.

PMID:1483625
Abstract

Considerable surgical progress of treating aortic dissection has been achieved during the past decade. The emergency indication for acute dissection of the ascending aorta (type A according to the Stanford classification) is unquestioned while surgical treatment for acute dissection of the descending aorta (type B dissection) is mainly reserved for complicated cases. The major complication of acute operations--fatal hemorrhage from the suture line and secondary multi-organ failure--have been successfully reduced by a progress of cardiopulmonary bypass techniques, the introduction of cold cardioplegic myocardial protection, the development of modern suture materials and glues and last not least by a continuous intensive monitoring. Especially the introduction of the so-called french glue safely enabled both the closure of the false lumen as well as the strong reinforcement of the diseased aortic wall and seems to offer a reliable alternative to the application of multi-layered teflon strips. Since the principle of all reconstructive approaches in case of dissection consists of closure of dissected layers and the limited replacement of the segment that is susceptible to a rupture the exact readaptation and reinforcement of the diseased aortic wall represents a fundamental operative step. In type A operations the supracoronary aortic prosthetic replacement or the combined replacement of ascending aorta plus aortic valve followed by the reattachment of coronary arteries has become the standard operative technique. In fact, independently from the location of the primary intimal tear the operation has been traditionally limited to replace the ascending aorta in order to remove an aortic segment that is most likely to rupture. Yet an increasing number of follow-up investigations has demonstrated recurrence of dissection or an aneurysmatical dilatation of the false lumen in about 20% of patients treated with ascending aortic replacement. Consequently, repair of the aortic transverse arch and the radical elimination of the intimal entry is now favoured by an increasing number of surgeons. In addition to these various perioperative and intraoperative adjuncts the introduction of new imaging techniques, especially computerized tomography, magnetic resonance imaging and transesophageal echocardiography allowed to establish adequate therapeutical concepts on a more rational basis. Transesophageal echocardiography as a mobile diagnostic device enables investigators to perform a bed-side dynamic visualization of both the location and extent of a dissection, the evaluation of ventricular performance and aortic competence. Treatment of acute type B dissection is mainly conservative unless complications like intractable pain, aneurysmatic enlargement of the false lumen, ischemia of visceral organs or even rupture occur.(ABSTRACT TRUNCATED AT 400 WORDS)

摘要

在过去十年中,主动脉夹层的外科治疗取得了显著进展。升主动脉急性夹层(根据斯坦福分类为A型)的急诊指征是毋庸置疑的,而降主动脉急性夹层(B型夹层)的外科治疗主要限于复杂病例。通过体外循环技术的进步、冷停跳心肌保护的引入、现代缝合材料和胶水的发展,以及持续的强化监测,急性手术的主要并发症——缝线处致命出血和继发性多器官功能衰竭——已成功减少。特别是所谓的法国胶水的引入,安全地实现了假腔的闭合以及病变主动脉壁的强力加固,似乎为多层特氟龙条带的应用提供了可靠的替代方案。由于夹层所有重建方法的原则包括封闭分离层以及有限地替换易破裂的节段,因此病变主动脉壁的精确重新适应和加固是一个基本的手术步骤。在A型手术中,冠状动脉上主动脉人工血管置换或升主动脉加主动脉瓣联合置换,随后重新连接冠状动脉已成为标准手术技术。事实上,传统上无论原发性内膜撕裂的位置如何,手术都局限于置换升主动脉,以切除最可能破裂的主动脉节段。然而,越来越多的随访研究表明,在接受升主动脉置换治疗的患者中,约20%出现夹层复发或假腔动脉瘤样扩张。因此,越来越多的外科医生倾向于修复主动脉横弓并彻底消除内膜入口。除了这些各种围手术期和术中辅助手段外,新成像技术的引入,特别是计算机断层扫描、磁共振成像和经食管超声心动图,使得能够在更合理的基础上建立适当的治疗概念。经食管超声心动图作为一种移动诊断设备,使研究人员能够在床边动态观察夹层的位置和范围、评估心室功能和主动脉瓣功能。除非出现顽固性疼痛、假腔动脉瘤样扩大、内脏器官缺血甚至破裂等并发症,急性B型夹层的治疗主要是保守治疗。

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