Pelletier G, Capdeville R, Mosnier H, Raymond J M, Delmont J, Moreaux J, Guivarch M, Amouretti M, Caroli F X, Levy V G
Department of Gastroenterology, Hôpital de Bicêtre, Le Kremlin Bicêtre, France.
J Hepatol. 1992 Sep;16(1-2):102-5. doi: 10.1016/s0168-8278(05)80101-1.
Piezoelectric lithotripsy with the EDAP LT-01 machine combined with adjuvant bile acid therapy results in complete clearance of radiolucent gallstones in selected patients. We assessed stone recurrence rate in 84 patients with complete clearance of stone fragments and followed up at least 12 months after cessation of bile acid therapy (mean 17 months, range 12-33). Fifty-four patients had a solitary stone and 30 multiple stones. Bile acid therapy was continued for 3 months after complete fragment stones clearance which was ascertained by two consecutive ultrasound examinations. Stone recurrence was assessed by ultrasonography at 6 and 12 months, and then at least once a year. Gallstone recurrence occurred in 5 patients (6%) between 9 and 12 months with no further recurrence up to 33 months. The rate of recurrence at one year was 3.7% in patients with a solitary stone and 10% in patients with multiple stones. Only one patient with stone recurrence had recurrent biliary pain. We concluded that early gallstone recurrence rate after successful lithotripsy seems to be low in patients with solitary stones.
使用EDAP LT-01机器进行的压电碎石术联合辅助胆汁酸治疗可使部分患者的透X线胆结石完全清除。我们评估了84例结石碎片完全清除的患者的结石复发率，并在胆汁酸治疗停止后至少随访12个月（平均17个月，范围12 - 33个月）。54例患者有单个结石，30例患者有多个结石。在连续两次超声检查确定结石碎片完全清除后，继续进行3个月的胆汁酸治疗。在6个月和12个月时通过超声检查评估结石复发情况，然后每年至少评估一次。5例患者（6%）在9至12个月之间出现胆结石复发，直至33个月均无进一步复发。单个结石患者一年的复发率为3.7%，多个结石患者为10%。只有1例结石复发患者有复发性胆绞痛。我们得出结论，对于单个结石患者，成功碎石术后早期胆结石复发率似乎较低。
