极北蝰蛇毒解酰胺酶活性的年龄变化
Age changes of Vipera berus venom amidolytic activity.
作者信息
Nedospasov A A, Rodina E V
机构信息
Institute of Molecular Genetics, Russian Academy of Sciences, Moscow.
出版信息
Toxicon. 1992 Nov;30(11):1505-8. doi: 10.1016/0041-0101(92)90530-i.
The study of age changes of amidolytic activity of Vipera berus venom is investigated using mixtures of chromogenic peptide substrates differing by detected groups. Quantities of venom (total protein content) and its proteolytic activity from snakes of different ages were compared. The venom composition of newly born adders was shown to be considerably different from the venom composition of young (12-month) adders of the same population. The next evolution of protease activity is weakly expressed.
利用不同检测基团的生色肽底物混合物，对极北蝰蛇毒酰胺分解活性的年龄变化进行了研究。比较了不同年龄蛇的毒液量（总蛋白含量）及其蛋白水解活性。结果表明，新生蝰蛇的毒液成分与同一种群中幼龄（12个月）蝰蛇的毒液成分有很大差异。蛋白酶活性的进一步演变表现较弱。
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